Abstract
Many organisms face the challenge of a changing environment. Individual cells in a multicellular organism face similar challenges. To cope with this, cells and organisms have developed the ability to mount transient responses in which subsets of genes appropriate to current conditions are activated for an appropriate time. One particularly well studied example of a transient response is provided by the heat-shock response (for general reviews see Lindquist, 1986; Lindquist and Craig, 1988). This induction of a small number of highly conserved proteins (known as the heat shock proteins or hsps) occurs when cultured cells or whole organisms are exposed to temperatures above their normal growth range. When the cells or organisms are returned to normal temperatures normal patterns of synthesis are restored.
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© 1990 Springer-Verlag Berlin Heidelberg
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Petersen, R.B., Lindquist, S. (1990). Differential mRNA Stability: A Regulatory Strategy for Hsp70 Synthesis. In: McCarthy, J.E.G., Tuite, M.F. (eds) Post-Transcriptional Control of Gene Expression. NATO ASI Series, vol 49. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75139-4_9
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DOI: https://doi.org/10.1007/978-3-642-75139-4_9
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