Abstract
This paper reviews our experiments using mouse cells transfected with human HLA class II sequences to study several aspects of antigen presentation, including: the production and screening of monoclonal antibodies; the roles of different HLA-DR2 class II loci products in presenting an M.Ieprae antigen to T cells; and, using transfectants super-transfected with ICAM-1, the effect of this accessory molecule on the T cell response.
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© 1990 Springer-Verlag Berlin Heidelberg
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Altmann, D.M., Wilkinson, D., Ikeda, H., Trowsdale, J. (1990). Dissection of the Roles of Specific Class II Antigens and Accessory Molecules in Antigen Presentation. In: Demaine, A.G., Banga, JP., McGregor, A.M. (eds) The Molecular Biology of Autoimmune Disease. NATO ASI Series, vol 38. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75133-2_8
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DOI: https://doi.org/10.1007/978-3-642-75133-2_8
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