Abstract
Myasthenia gravis (MG) is an antibody-mediated autoimmune disease of neuromuscular transmission, characterised by fatiguable weakness of striated muscle. Patients with MG show heterogeneity in clinical features, thymus pathology and HLA associations. For example, young onset cases are typically female, show hyperplasia of the thymus medulla and are very likely to have HLA-B8 and -DR3, the association being somewhat stronger with -B8 (Compston, Vincent, Newsom-Davis and Batchelor 1980).
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© 1990 Springer-Verlag Berlin Heidelberg
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Newsom-Davis, J., Harcourt, G., Beeson, D., Sommer, N., Vincent, A., Willcox, N. (1990). T Cell Reactivity to Acetylcholine Receptor in Myasthenia Gravis. In: Demaine, A.G., Banga, JP., McGregor, A.M. (eds) The Molecular Biology of Autoimmune Disease. NATO ASI Series, vol 38. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75133-2_33
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DOI: https://doi.org/10.1007/978-3-642-75133-2_33
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