Skip to main content

General Need for Quantitative Methodologies in Tissue Characterization by MRI

  • Conference paper
Tissue Characterization in MR Imaging
  • 122 Accesses

Abstract

The specific goal of tissue characterization using an imaging technique is the possibility of distinguishing in the image between a lesion and adjacent normal tissues, between benign and malignant neoplasias, and between primary tumors and metastases using special analysis procedures. The final objective is to improve diagnosis and prognosis and optimize therapy planning. Intrinsic multiparameter dependece is a peculiarity of magnetic resonance imaging (MRI), which provides both high tissue contrast flexibility and a possible special source of in vivo tissue characterization. A primary role in the expression of these features is played by MR spin-lattice and spin-spin relaxation times of tissues in the body.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abragam A (1961) The principles of nuclear magnetism. Clarendon, Oxford

    Google Scholar 

  • Beall PT, Sharad RA, Sitapati RK (1984) NMR data handbook for biomedical applications. Pergamon, New York

    Google Scholar 

  • Beneken JEW, Brown BH, Skupinski W (1985) Biomedical engineering programme of the European Community. J Med Eng Technol 9:61–68

    Article  PubMed  CAS  Google Scholar 

  • Bottomley PA, Foster TH, Argersinger RE, Pfeifer LM (1984) A review of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1–100 MHz: dependence of tissue type, NMR frequency, temperature, species, excision and age. Med Phys 11:425–448

    CAS  Google Scholar 

  • Bottomley PA, Hardy CJ, Argensinger RE, Allen-Moore G (1987) A review of H nuclear magnetic resonance relaxation in pathology: are T1 and T2 diagnostic? Med Phys 14:1–37

    Article  PubMed  CAS  Google Scholar 

  • Bydder GM (1987) Clinical use of contrast agents. In: Foster MA, Hutchison JMS. (eds) Practical NMR imaging. IRL Press, Washington, DC, pp 173–198

    Google Scholar 

  • Damadian R (1971) Tumor detection by NMR. Science 171:1151–1153

    Article  PubMed  CAS  Google Scholar 

  • EEC Concerted Research Project (1988a) Identification and characterization of biological tissues by NMR. Concerted research project of the European Economic Community. II. A protocol for in vitro proton rexalation studies. Magn Reson Imaging 6:179–184

    Article  Google Scholar 

  • EEC Concerted Research Project (1988b) Identification and characterization of biological tissues by NMR. Concerted research project of the European Economic Community. IV. Protocol and test objects for the assessment of MRI equipment. Magn Reson Imaging 6:195–199

    Article  Google Scholar 

  • Lerski RA, Orr JS (1987) Practical testing. In: Foster MA, Hutchison JMS. (eds) Practical NMR imaging. IRL, Press Washington, DC, pp 81–93

    Google Scholar 

  • Lerski RA, McRobbie DW, Straughan K, Walker PM, de Certaines JD, Bernard AM (1988) Identification and characterization of biological tissues by NMR. Concerted research project of the European Economic Community. V. Multi-center trial with protocols and prototype test objects for the assessment of MRI equipment. Magn Reson Imaging 6:201–214

    Article  PubMed  CAS  Google Scholar 

  • Mathur-De Vré R (1984) Biomedical implications of the relaxation behaviour of water related to NMR imaging. Br J Radiol 57:955–976

    Article  Google Scholar 

  • Mathur-De Vré R, Binet J, Bovee WMMJ, Foster MA (1988) Identification and characterization of biological tissues by NMR. Concerted research project of the European Economic Community. III. Multi-center trial with an in vitro NMR protocol. Magn Reson Imaging 6:185–194

    Article  Google Scholar 

  • Meiboom S, Gill D (1958) Modified spin echo method for measuring nuclear relaxation time. Rev Sci Instrum 29:688

    Article  CAS  Google Scholar 

  • Orr JS, Podo F (1988) Scientific report of the working group of the project and industry on harmonization of test procedures for performance assessment in MRI, Rome, 29 April, 1988, Eurospin Quarterly 17:21–115

    Google Scholar 

  • Podo F (1985) The European concerted research project on identification and characterization of biological tissues by nuclear magnetic resonance. J Med Eng Technol 9:117–122

    Article  PubMed  CAS  Google Scholar 

  • Podo F, Orr JS (eds) (1983) Proceedings of the EEC Workshop “Identification and characterization of biological tissues by NMR” Rome, 18–20 May, 1983. Ann 1st Super Sanita 19:1–214

    Google Scholar 

  • Podo F, Orr JS, Schmidt KH, Bovée WMMJ (1988) Identification and characterization of biological tissues by NMR. Concerted research project of the European Economic Community. I. Introduction, objectives and activities. Magn Reson Imaging 6:175–178

    Article  PubMed  CAS  Google Scholar 

  • Slichter CP (1963) Principles of magnetic resonance. Harper, New York

    Google Scholar 

  • Walker PM, Lerski RA, Mathur-De Vré R, Binet J, Yane F (1988) Identification and characterization of biological tissues by NMR. Concerted research project of the European Economic Community. VI. Preparation of agarose gels as reference substances for NMR relaxation time measurement. Magn Reson Imaging 6:215–222

    Article  PubMed  CAS  Google Scholar 

  • Young IR (1987) Development of tissue contrast in magnetic resonance imaging. In: Foster MA, Hutchison JMS. (eds) Practical NMR imaging. IRL Press, Washington, DC, pp 145–171

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Podo, F. (1990). General Need for Quantitative Methodologies in Tissue Characterization by MRI. In: Higer, H.P., Bielke, G. (eds) Tissue Characterization in MR Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74993-3_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-74993-3_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74995-7

  • Online ISBN: 978-3-642-74993-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics