Abstract
Administration of paramagnetic contrast agents provides for increased contrast and improvement in the detection and staging of a variety of lesions on T1-weighted spin-echo sequences. The underlying mechanism consists of shortening of the spin-lattice relaxation time of lesions which become highlighted on post-contrast T1-weighted images (McNamara 1987). This approach, however, may be suboptimal in lipid-rich regions and may fail when a lesion becomes isointense as a result of the overlapping relaxation times of enhanced lesion and lipid. For example, enhanced tumor within bone marrow may be undetectable using conventional T1-weighted spin-echo technique (Traill and Sartoris 1989).
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Szumowski, J., Simon, J.H., Totterman, S., Chacko, A. (1990). A Chemical Shift Imaging Strategy for Paramagnetic Contrast-Enhanced MRI. In: Higer, H.P., Bielke, G. (eds) Tissue Characterization in MR Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74993-3_17
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DOI: https://doi.org/10.1007/978-3-642-74993-3_17
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