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Development and Perspectives of the Human Lymphocyte Micronucleus Assay

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Advances in Mutagenesis Research

Part of the book series: Advances in Mutagenesis Research ((MUTAGENESIS,volume 1))

Abstract

The occurrence of micronuclei (MN) in plant cells after exposure to chemical substances and ionizing radiation has been a well-known phenomenon for several decades. These MN are smaller, accessory nuclear bodies in the cytoplasm which appear in addition to the main nucleus. They are believed to result primarily from acentric chromatin elements that were not incorporated into daughter nuclei during cell division. They may, however, also arise from whole chromosomes that failed to participate in normal anaphase movement.

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Authors and Affiliations

  1. Gesellschaft für Strahlen- und Umweltforschung, Institut für Strahlenbiologie, Ingolstädter Landstraße 1, D-8042, München-Neuherberg, Germany

    M. Bauchinger

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  1. R. Huber
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  2. M. Bauchinger
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  1. FB9 der Universität Gesamthochschule Essen, Universitätsstraße 5, Postfach 10 37 64, 4300, Essen 1, Germany

    Günter Obe

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© 1990 Springer-Verlag Berlin Heidelberg

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Huber, R., Bauchinger, M. (1990). Development and Perspectives of the Human Lymphocyte Micronucleus Assay. In: Obe, G. (eds) Advances in Mutagenesis Research. Advances in Mutagenesis Research, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74955-1_4

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  • DOI: https://doi.org/10.1007/978-3-642-74955-1_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74957-5

  • Online ISBN: 978-3-642-74955-1

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