Laboratory Research



Recent advances in laboratory research and their clinical application have enabled the clinician to reconcile clinical observations with related scientific observations of which the identification and detection of estrogen and progesterone receptor proteins in the cytosol of endometrial carcinoma have promoted hormone therapy; and it has been possible to estimate the prognosis in patients with endometrial carcinoma. The usefulness of monoclonal antibodies in making early diagnosis, and monitoring treatment and prognosis in patients with ovarian cancer is well demonstrated. Monoclonal antibodies have also been described in endometrial carcinoma. Cell cultures of gynecologic cancers in vivo and in vitro have a long history and have contributed to cytobiologic research of gynecologic neoplasia. In this chapter, an attempt will be made to describe in some detail the current knowledge concerning steroid hormone receptor and monoclonal antibody, which have been studied in patients with gynecologic cancers.


Estrogen Receptor Progesterone Receptor Endometrial Carcinoma Steroid Receptor Granulosa Cell Tumor 
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© The People’s Medical Publishing House Beijing and Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  1. 1.Gynecologic Oncology DepartmentCancer Institute (Hospital) Chinese Academy of Medical SciencesBeijingP.R.China

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