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Cachectin/Tumor Necrosis Factor and Lymphotoxin

  • B. Beutler
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 95 / 2)

Abstract

As it acts to eradicate viruses, bacteria, and parasitic pathogens, the host immune system may sometimes prove to be a liability rather than an asset. The inflammatory response to invasive organisms may injure the host as surely as the organisms themselves, and, in many instances, the immune response is itself a major pathogenetic vehicle. Thus, physicians strive to temper the immune response in their attempts to manage some infectious disease states. At present, this is achieved through the use of glucocorticosteroids and, occasionally, cytotoxic drugs.

Keywords

Tumor Necrosis Factor Human Tumor Necrosis Factor Hemorrhagic Necrosis Recombinant Tumor Necrosis Factor Recombinant Human Tumor Necrosis Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1990

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  • B. Beutler

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