Role of Growth Factors in Cartilage and Bone Metabolism

  • J. Pfeilschifter
  • L. Bonewald
  • G. R. Mundy
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 95 / 2)


Bone is subject to extensive modeling and remodeling processes throughout life. These processes start with the endochondral and membranous formation of bone tissue during embryonic life, dominate the period of postnatal bone growth, and persist as constant cycles of removal of old bone and replacement by new bone long after the bones have ceased to grow. Size, shape, and structure of bone is determined by these processes.


Growth Hormone Local Growth Factor Bone Organ Culture Multiplication Stimulate Activity Growth Honnone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • J. Pfeilschifter
  • L. Bonewald
  • G. R. Mundy

There are no affiliations available

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