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Transformation of Cells in Culture

  • Chapter
Chemical Carcinogenesis and Mutagenesis I

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 94 / 1))

Abstract

Our understanding of the aetiology and development of neoplasia centres around our knowledge of the behaviour or mammalian cells and their transformed counterparts. Fundamental cancer research today aims to define precisely the molecular lesions which distinguish the “normal” from the “malignant” cell and to determine how these affect cellular behaviour in vivo. When these mechanisms are elucidated we will have the basis for a more rational design of diagnostic and prognostic tests and of the therapeutic agents.

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  1. M. A. Knowles
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  1. Chester Beatty Laboratories, The Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, SW3 6JB, London, Great Britain

    Colin S. Cooper Ph.D.  & Philip L. Grover D.Sc.  & 

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Knowles, M.A. (1990). Transformation of Cells in Culture. In: Cooper, C.S., Grover, P.L. (eds) Chemical Carcinogenesis and Mutagenesis I. Handbook of Experimental Pharmacology, vol 94 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74775-5_7

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