Summary
Bone mineral content was measured by dual photon-absorption densitometry (DPA) in 66 patients of either sex (aged 13–58 years) with bronchial asthma being on long-term steroid treatment for at least two years. The results of DPA were correlated with the evaluation of questionnaire covering the main demographic data. Out of all patients 33.3% displayed a diminished bone mass in L2-L3 (female 40.5%; male 20.8%). Excluding female patients in the post-menopause, only 22.7% of the remaining female patients showed a loss in bone density. Since only a minority of patients with chronic asthma being on long-term corticoid treatment develop signs of osteoporosis, the risk patients being prone to a corticoid related bone tissue loss have to be detected. DPA appears to be a very sensitive method for routine screening of asthmatics on corticoids.
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Literatur
Adinoff AD, Hollister JR (1983) Steroid induced fractures and bone loss in patients with asthma. N Engl J Med 309:265–268
Heuck F (1967) Radiologische Aspekte der Osteoporose. Dtsch Med Wochenschr 92:2272–2277
Kapp S (1986) Messung des KMG mit der Zweistrahl-Photonenabsorptionsmethode zur Quantifizierung der Osteoporose. ÄRP 11:585–594
Katz RD (1985) Recent advances in the early diagnosis of osteoporosis. A review. MMJ 34:889–895
Kessler D, Meister W (1985) Untersuchungen zur Osteoporose bei Kortikoidtherapie von Patienten mit chron. obstruktiven Atemwegserkrankungen. Z Erkrank Atm-Org 165:248–254
Krokowski E (1968) Die röntgenologische Substanzanalyse des Knochens. Prinzip u. praktische Durchführung. Fortschr Röntgenstr 108:394–400
Krokowski E (1972) Kortikoid-Osteoporose. Medizinische Klinik 36:1149–1157
Mueller MN (1976) Effects of corticosteroids on bone mineral in rheumatic arthritis and asthma. AJR 126:1300
Ringe JD, Wanner HW (1986) Früherkennung der Osteoporose. Dtsch med Wschr 111:954–958
Seidin DW, Esser PD, Alderson PO (1988) Comparison of bone density measurements from different skeletal sites. J Nucl Med 29:168–173
Ziegler R (1988) Klinik der Glucocorticoidinduzierten Osteoporose. IV. Arbeitstagung der Sektion Calciumregulierende Hormone und Knochenstoffwechsel der deutschen Gesellschaft für Endokrinologie, Hamburg
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© 1989 Springer-Verlag · Heidelberg
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Dohm, K., Semler, J. (1989). Bestimmung der Knochendichte mittels Doppelphotonenabsorptionsmessung (DPA) bei Patienten mit Asthma bronchiale unter Kortikoiddauertherapie. In: Willert, HG., Heuck, F.H.W. (eds) Neuere Ergebnisse in der Osteologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74770-0_81
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DOI: https://doi.org/10.1007/978-3-642-74770-0_81
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