Abstract
The current therapy for breast cancer must involve an integrated surgical, radiotherapeutic and chemotherapeutic approach. Disease-free survival and death are common end points used to evaluate treatment efficacy. However, other end points deserve consideration for patients undergoing breast conservation therapy. For these patinets, successful therapy must maximize locoregional (LR) control without compromising cosmesis. Likewise, when adjuvant treatment is given after a mastectomy, or when radiotherapy is utilized as the primary treatment in locally advanced breast cancer, the probability of LR recurrence must be considered.
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Robertson, J.M., Clarke, D.H., Martinez, A. (1991). The Role of Radiation Therapy in High-Risk Breast Cancer. In: Ragaz, J., Ariel, I.M. (eds) High-Risk Breast Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74728-1_8
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