Abstract
Koleč, the detached laboratories and experimental animal farm of the Institute for Experimental Biology and Genetics is some 10 miles northwest of Prague. A green graduate in 1968, I spent the very first year of my research apprenticeship there. My task was to produce sera for typing of chicken blood group antigens, which turned out to be the B locus. I recall chasing the birds around their outside runs to be bled, immunised and bled again, through the changing seasons and fortunes of that historic year. I acquired an allergy to the uncooperative dirty beasts but, in compensation, also a lasting appreciation of serology as a tool of genetic analysis.
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References
Boyd MF, Stratman-Thomas WK, Kitchen SF (1936) On acquired immunity to Plasmodium falciparum. Am J Trop Med 16:139–145
Cadigan FC, Chaicumpa V Jr (1969) Plasmodium falciparum in the white-handed gibbon: protection afforded by previous infection with homologous and heterologous strains obtained in Thailand. Military Med 134: 1135–1139
Clark JT, Donachie S, Anand R, Wilson CF, Heidrich HG, McBride JS (1989) 46-53 Kilodalton glycoprotein from the surface of Plasmodium falciparum merozoites. Mol Biochem Parasitol 32: 15–24
Fenton B, Clark JT, Wilson CF, McBride JS, Walliker D (1989) Polymorphism of a 35-48kDa Plasmodium falciparum merozoite surface antigen. Mol Biochem Parasitol 34: 79–86
Greenwood BM, Bradley AK, Greenwood AM, Byass P, Jammeh H, Marsh K, Tulloch S, Old-field FSJ, Hayes R (1987) Mortality and morbidity from malaria among children in a rural area of The Gambia, West Africa. Trans Soc Trop Med Hyg 81: 478–486
James SP, Nicol WD, Shute PG (1932) A study of induced malignant tertian malaria. Proc R Soc Med 25: 1153–1181
McBride JS, Walliker D, Morgan D (1982) Antigenic diversity in the human malaria parasite Plasmodium falciparum. Science 217: 254–257
McBride JS, Newbold CI, Anand R (1985) Polymorphism of a high molecular weight schizont antigen of the human malaria parasite Plasmodium falciparum. J Exp Med 161: 160–180
Miller LH, Howard RJ, Carter R, Good MF, Nussenzweig V, Nussenzweig RS (1986) Research towards malaria vaccines. Science 234: 1349–1356
Smythe JA, Goppel RL, Brown GV, Ramasamy R, Kemp DJ, Anders RF (1988) Identification of two integral membrane proteins of Plasmodium falciparum. Proc Nat Acad Sci USA, 85: 5195–5199
Stárchler D (1989) How much malaria is there worldwide? Parasitol Today 5: 39–40
Walliker D, Quakyi IA, Wellems TE, McCutchan TF, Szarfman A, London WT, Corcoran LM, Burkot TR, Carter R (1987) Genetic analysis of the human malaria parasite Plasmodium falciparum. Science 236: 1661–1666
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© 1989 Springer-Verlag Berlin Heidelberg
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McBride, J.S. (1989). From Serology of the Chicken MHC to Polymorphism of Malaria Antigen Genes. In: Ivanyi, P. (eds) Realm of Tolerance. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74712-0_18
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DOI: https://doi.org/10.1007/978-3-642-74712-0_18
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