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Menstrual Disturbances Caused by Exercise

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The Menstrual Cycle and Its Disorders

Abstract

Despite its complexity, the rhythmic pattern of hormonal changes which together form the menstrual cycle is relatively robust. The prevalence of amenorrhea and oligomenorrhea in the general population approximate 2% and 5% respectively (Drew 1961; Sher 1942; Petterson and Fries 1973). The report that up to one-half of women collegiate distance runners may be amenorrheic (Feicht et al. 1978) was in contrast to the image that “exercise is good for you.”

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References

  • Baanders-Van Halewin EA, de Ward F (1968) Menstrual cycles shortly after menarche in European and Bantu girls. Hum Biol 40: 314–322

    Google Scholar 

  • Baker ER, Mathur RS, Kirk RF, Williamson HO (1981) Female runners and secondary amenorrhea: correlation with age, parity, mileage and plasma hormones and sex-hormone-binding globulin. Fertil Steril 36: 183–187

    PubMed  CAS  Google Scholar 

  • Beumont PJV, George GCW, Pimstone BL, Vinik AI (1976) Body weight and the pituitary response to hypothalamic releasing hormones. J Clin Endocrinol Metab 43: 487–496

    Article  PubMed  CAS  Google Scholar 

  • Billewicz WS, Fellowes HM, Hytten CY (1976) Comments on the critical metabolic mass and the age of menarche. Ann Hum Biol 3: 51–59

    Article  PubMed  CAS  Google Scholar 

  • Bojilen K, Bentzoin M (1968) Influence of climate and nutrition on age at menarche: a historical review and a modern hypothesis. Hum Biol 40: 69–85

    PubMed  CAS  Google Scholar 

  • Bonen A, Belcastro AN, Ling WY, Simpson AA (1981) Profiles of selected hormones during the menstrual cycles of teenage athletes. J Appl Physiol 50: 545–551

    PubMed  CAS  Google Scholar 

  • Boyden TW, Pamenter RW, Grosso D, Stanforth P, Rotkis T, Wilmore JH (1982) Prolactin responses, menstrual cycles, and body composition of women runners. J Clin Endocrinol Metab 54: 711–714

    Article  PubMed  CAS  Google Scholar 

  • Boyden TW, Pamenter RW, Stanforth P, Rotkis T, Wilmore JH (1983) Sex steroids and endurance running in women runners. Fertil Steril 39: 629–632

    PubMed  CAS  Google Scholar 

  • Boyden TW, Pamenter RW, Stanforth P, Rotkis TC, Wilmore JH (1984) Impaired gonadotropin responses to gonadotropin stimulating hormone in endurance trained women. Fertil Steril 41: 359–363

    PubMed  CAS  Google Scholar 

  • Brooks SM, Sanborn CF, Albrecht BH, Wagner WW (1984) Diet in athletic amenorrhea. Lancet 1: 559–560 (letter)

    Article  PubMed  CAS  Google Scholar 

  • Brown PE (1966) The age at menarche. Br J Soc Prev Med 20: 9–14

    Google Scholar 

  • Bullen BA, Skrinar GS, Beitins IZ, von Mering G, Turnbull BA, McArthur JW (1985) Induction of menstrual disorders by strenuous exercise in untrained women. N Engl J Med 312: 1349–1353

    Article  PubMed  CAS  Google Scholar 

  • Carlberg KA, Buckman MT, Peake GT, Riedesel ML (1983) Body composition of oligo/amenorrheic athletes. Med Sci Sports Exerc 15: 215–217

    PubMed  CAS  Google Scholar 

  • Chakravarty I, Sreedhar R, Ghosh KK, Bulusu S (1982) Circulating gonadotropin profile in severe cases of protein calorie malnutrition. Fertil Steril 37: 650–654

    PubMed  CAS  Google Scholar 

  • Copeland PC, Paunier L, Sizonenko PC (1977) The secretion of adrenal androgens and growth patterns of patients with hypogonadotropic hypogonadism. J Pediatr 91: 985–990

    Article  PubMed  CAS  Google Scholar 

  • Cumming DC, Rebar RW (1983) Effects of exertion on reproductive function. Am J Indust Med 5: 113–125

    Article  Google Scholar 

  • Cumming DC, Rebar RW (1984) Lack of consistency in the indirect methods of estimating body fat. Fertil Steril 41: 739–772

    PubMed  CAS  Google Scholar 

  • Cumming DC, Rebar RW (1985) Hormonal changes with acute exercise and with training in women. Semin Reprod Endocrinol 3: 55–64

    Article  CAS  Google Scholar 

  • Cumming DC, Wheeler GD (1987) Endorphins and exercise. Semin Reprod Endocrinol 5: 171–179

    Article  Google Scholar 

  • Cumming DC, Rebar RW, Hopper BR, Yen SSC (1982) Evidence for an influence of the ovary on adrenal steroidogenesis. J Clin Endocrinol Metab 54: 69–71

    Article  Google Scholar 

  • Cumming DC, Vickovic MM, Wall SR, Fluker MR (1985a) Defects in pulsatile LH release in normally menstruating runners. J Clin Endocrinol Metab 60: 810–812

    Article  PubMed  CAS  Google Scholar 

  • Cumming DC, Vickovic MM, Wall SR, Fluker MR, Belcastro AN (1985b) The effect of acute exercise on pulsatile release of luteinizing hormone in women runners. Am J Obstet Gynecol 153: 482–485

    PubMed  CAS  Google Scholar 

  • Dale E, Gerlach DH, Wilhite AL (1979) Menstrual dysfunction in distance runners. Obstet Gynecol 54: 47–53

    Article  PubMed  CAS  Google Scholar 

  • Deuster PA, Kylem SB, Moser PB, Vigersky RA, Singh A, Schoomaker EB (1986) Nutritional intakes and status of highly trained amenorrheic and eumenorrheic women runners. Fertil Steril 46: 636–643

    PubMed  CAS  Google Scholar 

  • Dixon G, Eurman P, Stern B, Schwartz B, Rebar RW (1984) Hypothalamic function in amenorrheic runners. Fertil Steril 42: 377–383

    PubMed  CAS  Google Scholar 

  • Dreizen S, Spirakis CN, Stone RE (1967) A comparison of skeletal growth and maturation in undernourished and well nourished girls before and after menarche. J Pediatr 70: 256–263

    Article  PubMed  CAS  Google Scholar 

  • Drew FL (1961) The epidemiology of secondary amenorrhea. J Chronic Dis 14: 396–401

    Article  PubMed  CAS  Google Scholar 

  • Ellison PT, Lager C (1985) Exercise-induced menstrual disorders. N Engl J Med 313: 825–826

    Google Scholar 

  • Espenschade A (1940) Motor performance in adolescence. Monogr Soc Res Child Dev 5: 1–126

    Article  Google Scholar 

  • Feicht CB, Johnson TS, Martin BJ, Sparkes KE, Wagner WW Jr (1978) Secondary amenorrhoea in athletes. Lancet 2: 1145–1146

    Article  PubMed  CAS  Google Scholar 

  • Fries H, Nillius SJ, Petterson F (1974) Epidemiology of secondary amenorrhea. Am J Obstet Gynecol 118: 473–479

    PubMed  CAS  Google Scholar 

  • Frisch RE (1985) Body fat, menarche and reproductive ability. Semin Reprod Endocrinol 3: 45–54

    Article  Google Scholar 

  • Frisch RE, Revelle R (1971) Height and weight at menarche and hypothesis of critical body weights and adolescent events. Science 169: 397–399

    Article  Google Scholar 

  • Frisch RE, Wishak G, Vincent L (1980) Delayed menarche and amenorrhea in ballet dancers. N Engl J Med 303: 17–19

    Article  PubMed  CAS  Google Scholar 

  • Frisch RE, Gotz-Welbergen AV, McArthur JW, Albright TE, Witischi J, Bullen B, Birnholtz J, Reed RB, Hermann H (1981) Delayed menarche and amenorrhea of college athletes in relation to age of onset of training. JAMA 246: 1559–1563

    Article  PubMed  CAS  Google Scholar 

  • Galle PC, Freeman EW, Galle MG, Huggins GR, Sondheimer SJ (1983) Physiologic and psychologic profiles in a survey of women runners. Fertil Steril 39: 633–639

    PubMed  CAS  Google Scholar 

  • Glass AR, Yahiro JA, Deuster PA, Vigersky RA, Kyle SB, Schoomaker EB (1987) Amenorrhea in Olympic marathon runners. Fertil Steril 48: 740–745

    PubMed  CAS  Google Scholar 

  • Grossman A, Moult PJA, Gaillard RC, Delitala G, Toff WD, Rees LH, Besser GM (1981) The opioid control of LH and FSH release: effects of a met-enkephalin analogue and naloxone. Clin Endocrinol 14: 41–47

    Article  CAS  Google Scholar 

  • Johnston FE, Roche AF, Schell LM, Wettenhall NB (1975) Critical weight at menarche: critique of a hypothesis. Am J Dis Child 129: 19–23

    PubMed  CAS  Google Scholar 

  • Kantero RL, Widholm O (1971) The age of menarche in Finnish girls in 1969. Acta Obstet Gynaecol Scand [Suppl] 14: 7–18

    Article  Google Scholar 

  • Kennedy GC (1969) Interactions between feeding behaviour and hormones during growth. Ann NY Acad Sci 157: 1049–1061

    Article  PubMed  CAS  Google Scholar 

  • Kirkwood RF, Cumming DC, Aherne FX (1987) Nutrition and puberty in the female. Proc Soc Nutr 46: 177–192

    Article  CAS  Google Scholar 

  • Kulin HE, Bwibo N, Mutie D, Santner SJ (1984) Gonadotropin excretion during puberty in mal-nourished children. J Pediatr 105: 325–328

    Article  PubMed  CAS  Google Scholar 

  • Lloyd T, Buchanan JR, Bitzer S, Waldman CJ, Myers C, Ford BG (1987) Interrelationships of diet, athletic activity, menstrual status and bone density among collegiate women. Am J Clin Nutr 46: 681–684

    PubMed  CAS  Google Scholar 

  • Lutter JM, Cushman S (1982) Menstrual patterns in female runners. Phys Sportsmed 10 (9): 60–72

    Google Scholar 

  • Malina RM, Harper AB, Avent HH, Campbell DE (1973) Age at menarche in athletes and non-athletes. Med Sci Sports Exerc 5: 11–13

    CAS  Google Scholar 

  • Malina RM, Spirduso WW, Tate C, Baylor AM (1978) Age at menarche and selected menstrual characteristics in athletes at different competitive levels and in different sports. Med Sci Sports Exerc 10: 218–222

    CAS  Google Scholar 

  • Malina RM, Bouchard C, Shoup RF, Demiijian A, Lariviere G (1979) Age at menarche, family size and birth order in athletes at the Olympic Games, 1976. Med Sci Sports Exerc 11: 354–358

    CAS  Google Scholar 

  • McArthur JW, Bullen BH, Beitins IZ, Pagano M, Badger TM, Klibanski A (1980) Hypothalamic amenorrhea in runners of normal body composition. Endocr Res Commun 7: 13–25

    Article  PubMed  CAS  Google Scholar 

  • McNeill D, Livson N (1963) Maturation rate and body build in women. Child Dev 34: 25–32

    PubMed  CAS  Google Scholar 

  • Nakao K, Nakai Y, Oki S, Matsubara S, Konishi T, Nishitani H, Imura H (1980) Immuno-reactive β-endorphin in human cerebrospinal fluid. J Clin Endocrinol Metab 50: 230–233

    Article  PubMed  CAS  Google Scholar 

  • Petterson F, Fries H (1973) Epidemiology of secondary amenorrhea. Am J Obstet Gynecol 117: 80–86

    Google Scholar 

  • Prior JC (1982a) Menstrual cycle changes with training: anovulation and short luteal phase. Can J Appl Sports Sci 7: 173–177

    CAS  Google Scholar 

  • Prior JC (1982b) Endocrine “conditioning” with endurance training. Can J Appl Sports Sci 7: 148–157

    CAS  Google Scholar 

  • Prior JC, Ho Yuen B, Clement P, Thomas J (1982) Reversible luteal phase changes associated with marathon training. Lancet 1: 269–270

    Article  Google Scholar 

  • Rappoport SI, Klee WA, Pettigrew KD, Ohno K (1980) Entry of opioid peptides into the central nervous system. Science 207: 84–86

    Article  Google Scholar 

  • Rebar RW, Cumming DC (1981) Reproductive function in women athletes. JAMA 246: 1590

    Article  PubMed  CAS  Google Scholar 

  • Reeves J (1979) Estimating fatness. Science 204: 881

    Article  PubMed  CAS  Google Scholar 

  • Reid RL, Hoff JD, Yen SSC, Li CH (1981) Effects of exogenous βh-endorphin on pituitary hormone secretion and disappearance rate in normal human subjects. J Clin Endocrinol Metab 52: 1179–1184

    Article  PubMed  CAS  Google Scholar 

  • Ronkainen H (1985) Depressed follicle stimulating hormone, luteinizing hormone, and prolactin responses to the luteinizing hormone releasing hormone, thyrotropin-releasing hormone, and metoelopramide test in endurance runners in the hard-training season. Fertil Steril 44: 755–759

    PubMed  CAS  Google Scholar 

  • Ronkainen H, Pakarinen A, Kirkinen P, Kauppila A J (1985) Physical exercise-induced changes and season-associated differences in the pituitary-ovarian function of runners and joggers. J Clin Endocrinol Metab 60: 416–422

    Article  PubMed  CAS  Google Scholar 

  • Russell JB, Mitchell D, Musey PI, Collins DC (1984a) The relationship of exercise to anovulatory cycles in female athletes: hormonal and physical characteristics. Obstet Gynecol 63: 452–456

    PubMed  CAS  Google Scholar 

  • Russell JB, Mitchell D, Musey PI, Collins DC (1984b) The role of β-endorphin and catechol-estrogens on the hypothalamic-pituitary axis in female athletes. Fertil Steril 42: 690–695

    PubMed  CAS  Google Scholar 

  • Schwartz B, Cumming DC, Riordan E, Selye M, Yen SSC, Rebar RW (1981) Exercise associated amenorrhea: a disticnt entity? Am J Obstet Gynecol 1141: 662–670

    Google Scholar 

  • Schweiger UF, Herman R, Laessle W, Riedel M, Schweiger M, Pirke KM (1988) Caloric intake, stress and menstrual function in athletes. Fertil Steril 49: 447–450

    PubMed  CAS  Google Scholar 

  • Shangold MM, Levine HS (1982) The effect of marathon training on menstrual function. Am J Obstet Gynecol 143: 862–869

    PubMed  CAS  Google Scholar 

  • Shangold MM, Freeman R, Thysen B, Gatz M (1979) The relationship between long-distance running, plasma progesterone and luteal phase length. Fertil Steril 31: 130–133

    PubMed  CAS  Google Scholar 

  • Sher N (1942) Causes of delayed menstruation and its treatment. Br Med J 1: 347–349

    Article  Google Scholar 

  • Speroff L, Redwine DB (1979) Exercise and menstrual dysfunction. Phys Sportsmed 8 (5): 42–52

    Google Scholar 

  • Stein Z, Susser M (1975) Fertility, fecundity, famine: food rations in the Dutch famine 1944/5 have a causal relationship to fertility and probably to fecundity. Hum Biol 47: 131–154

    PubMed  CAS  Google Scholar 

  • Steiner RA (1987) Nutritional and metabolic factors in the regulation of reproductive hormone secretion in the primate. Proc Nutr Soc 46: 159–175

    Article  PubMed  CAS  Google Scholar 

  • Stubbs WA, Jones A, Edwards CRW, Delitala G, Jeffcoate WJ, Ratter SJ, Besser GM, Bloom SR, Alberti KGMM (1978) Hormonal and metabolic responses to an enkephalin analogue in normal man. Lancet 2: 1225–1227

    Article  PubMed  CAS  Google Scholar 

  • Tanner JM (1962) Growth at adolescence, 2nd edn. Blackwell Scientific, Philadelphia

    Google Scholar 

  • Trussel J (1978) Menarche and fatness: a re-examination of the critical body composition hypothesis. Science 200: 1506–1509

    Article  Google Scholar 

  • Van Loon GR (1983) Plasma dopamine: regulation and significance. Fed Proc 42: 3012–3018

    PubMed  Google Scholar 

  • Veldhuis JD, Evans WS, Demers LM, Thorner MO, Wakat D, Rogol AD (1985) Altered neuroendocrine regulation of gonadotropin secretion in women distance runners. J Clin Endocrinol Metab 61: 557–563

    Article  PubMed  CAS  Google Scholar 

  • Vigersky RA, Andersen AE, Thompson RH, Loriaux DL (1977) Hypothalamic dysfunction in secondary amenorrhea associated with simple weight loss. N Engl J Med 297: 1141–1145

    Article  PubMed  CAS  Google Scholar 

  • Villanueva AL, Schlosser C, Hopper B, Liu JH, Hoffman DI, Rebar RW (1986) Increased Cortisol production in women runners. J Clin Endocrinol Metab 63: 133–136

    Article  PubMed  CAS  Google Scholar 

  • Wakat DK, Sweeney KA, Rogol AD (1978) Reproductive system function in women cross country runners. Med Sci Sports Exerc 14: 263–269

    Google Scholar 

  • Warren MP (1980) The effects of exercise on pubertal progression and reproductive function in girls. J Clin Endocrinol Metab 51: 1150–1157

    Article  PubMed  CAS  Google Scholar 

  • Weir J, Dunn JE Jr, Jones EG (1971) Race and age at menarche. Am J Obstet Gynecol 111: 594–596

    PubMed  CAS  Google Scholar 

  • Wiler JC, Boureau F, Dauthier, Bonora M (1979) Study of naloxone in normal awake man: effects on heart rate and respiration. Neuropharmacology 18: 469–472

    Article  Google Scholar 

  • Wolanski N (1968) Environmental modification of human form and function. Ann NY Acad Sci 134: 826–840

    Article  Google Scholar 

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© 1989 Springer-Verlag Berlin Heidelberg

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Cumming, D.C. (1989). Menstrual Disturbances Caused by Exercise. In: Pirke, K.M., Wuttke, W., Schweiger, U. (eds) The Menstrual Cycle and Its Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74631-4_16

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  • DOI: https://doi.org/10.1007/978-3-642-74631-4_16

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