Abstract
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a regulatory glycoprotein necessary for the proliferation, maturation, and survival of myeloid cells [4]. Myelopoiesis is enhanced when recombinant human (rh) GM-CSF is given to mice, monkeys [6], and some patients with various forms of neutropenia [3, 5]. The clinical use of rhGM-CSF infusions is under intensive investigation now.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Afanasyev BV, Tiranova SA, Kulibaba TG, Zubarovskaya LS, Bolshakova GD, Zabelina TS (1983) Cloning of human hemopoietic cells in the “agar drop-liquid medium” system. Ther Arch (USSR) 8: 114
Golde DW, Cline MJ (1973) Growth of human bone marrow in liquid culture. Blood 41: 45
Groopman JE, Mitsuyasu RT, DeLeo MJ, Oette DH, Golde DW (1987) Effect of recombinant human granulocyte macrophage colony stimulating factor on myelopoiesis in the acquired immunodeficiency syndrom. N Engl J Med 317: 593
Metealf D (1977) Haemopoietic colonies. Springer,Berlin Heidelberg New York
Nemunaitis J, Singer JW, Buckner CD, Hill R, Storb R, Thomas ED, Appelbaum FR (1988) Use of recombinant human granulocyte macrophage colony stimulating factor (rh GM-CSF) in autologous marrow transplantation for lymphoid malignancies. Blood 72: 834
Nienhuis AW, Donahue RE, Karisson S, Clark SC, Agricola B, Antihoff N, Pierce JE, Turner P, Anderson WF, Nathan DG (1987) Recombinant human granulocyte macrophage colony stimulating factor ( GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. J Clin Invest 80: 573
Pierce GB (1983) The cancer cell and its control by the embryo. Am J Pathol 113: 117
Zubarovskaya LS, Afanasyev BV, Smirnova G A, Lukasheva TN, Patterson D, Shishkov AL, Balayan LN, Ostrovsky AM (1985) Colony-stimulating activity of bone marrow trephanobiopsies of patients with different pathological conditions of the blood system. Ther Arch (USSR) 7: 22
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Afanasyev, B.V., Shatrov, V.A., Balayan, N. (1989). The Effect of Human and Rat Fetal Bone on Hematopoiesis In Vitro and In Vivo. In: Neth, R., et al. Modern Trends in Human Leukemia VIII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74621-5_31
Download citation
DOI: https://doi.org/10.1007/978-3-642-74621-5_31
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-50967-7
Online ISBN: 978-3-642-74621-5
eBook Packages: Springer Book Archive