Advertisement

Expression of Cell Differentiation Antigens as a Prognostic Factor in Acute Leukemia

  • J. Hołowiecki
  • D. Lutz
  • V. Callea
  • M. Brugiatelli
  • S. Krzemień
  • B. Stella-Hołowiecka
  • A. Neri
  • R. Ihle
  • V. Schranz
  • F. Graf
  • G. Kelenyi
  • K. Jagoda
  • F. Zintl
  • T. Reves
  • G. Kardos
  • S. Barceanu
Conference paper
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 32)

Abstract

Much attention has been devoted to the study of prognostic factors in acute leukemia. Most of the published studies have been concerned with easily measured clinical and hematological parameters [6, 8] while studies requiring specialized techniques such as chromosome or molecular analysis [9] and immunophenotyping of leukemia [1–3, 7] have generally been rare.

Keywords

Acute Myeloid Leukemia Acute Leukemia Complete remISSIOn Rate Cell Differentiation Antigen Acute Nonlymphocytic Leukemia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Dinndorf PA, Andrews RG, Benjamin D, Ridgway D, Wolff L, Bernstein ID (1986) Expression of normal myeloid-associated antigens by acute leukemia cells. Blood 67: 1048–1052PubMedGoogle Scholar
  2. 2.
    Greaves M, Janossy G, Peto J, Kay H (1981) Immunologically defined subclasses of ALL in children: their relationship to presentation features and prognosis. Br J Haematol 48: 179PubMedGoogle Scholar
  3. 3.
    Griffin JD, Davis R, Nelson DA, Davey FR, Mayer RJ, Schiffer C, Mclntyre OR, Bloomfield CD (1986) Use of surface marker analysis to predict outcome of adult acute myeloblastic leukemia. Blood 68: 1232–1241PubMedGoogle Scholar
  4. 4.
    Hotowiecki J, Lutz D, Krzemien S, Stella-Holowiecka B, Graf F, Kelenyi G, Schranz V, Callea V, Brugiatelli M, Neri A, Magyarlaki T, Ihle R, Jagoda K, Rudzka E (1986) CD-I 5 antigen detected by the VIM-D5 monoclonal antibody for prediction of ability to achieve complete remission in acute nonlymphocytic leukemia. Acta Haematol (Basel) 76: 16–19CrossRefGoogle Scholar
  5. 5.
    Knapp W, Majdic O, Stockinger H, Bettelheim P, Liszka L, Koller U, Peschel C (1984) Monoclonal antibodies to human myelomonocyte differentiation antigen in the diagnosis of acute myeloid leukemia. Med Oncol Tumor Pharmacother 1: 257–262PubMedGoogle Scholar
  6. 6.
    Mertelsman K, Thaler H, To L, Gee Ts, McKenzie S, Schauer P, Friedman A, Arlin] Z, Cirrincione C, Clarkson B (1980) Morphological classification, response to therapy and survival in 263 adult patients with acute non-lymphoblastic leukemia. Blood\ 56: 773–781Google Scholar
  7. 7.
    Ryan DH, Chappie CW, Kossover SA, Sandberg AA, Cohen HJ (1987) Phenotypic similarities and differences between; CALLA-positive B-cell precursors. Blood. 70: 814–821PubMedGoogle Scholar
  8. 8.
    Swirsky DM, DeBastos M, Parish SE, Rees JKH, Hayhoe FGJ (1986) Features affecting outcome during remission induction of acute myeloid leukaemia in 619 adult patients. Br J Haematol 64: 435–453PubMedCrossRefGoogle Scholar
  9. 9.
    Yunis J, Brunning R, Howe R, Lobell M (1984) High-resolution chromosomes as an independent prognostic indicator in adult acute non-lymphocytic leukemia. N Engl J Med 311: 812–818PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • J. Hołowiecki
    • 2
  • D. Lutz
    • 3
  • V. Callea
    • 4
  • M. Brugiatelli
    • 4
  • S. Krzemień
    • 2
  • B. Stella-Hołowiecka
    • 2
  • A. Neri
    • 4
  • R. Ihle
    • 5
  • V. Schranz
    • 6
  • F. Graf
    • 6
  • G. Kelenyi
    • 8
  • K. Jagoda
    • 2
  • F. Zintl
    • 9
  • T. Reves
    • 7
  • G. Kardos
    • 6
  • S. Barceanu
    • 1
  1. 1.Union des SocietésDes Sciences MédicalesBucarestRomania
  2. 2.Department of HaematologySilesian Medical AcademyReymonta 8Poland
  3. 3.Ludwig-Boltzmann-Institut für Leukämieforschung und HämatologieHanusch-KrankenhausViennaAustria
  4. 4.Div. di EmatologiaOspedale RiunitiReggio CalabriaItaly
  5. 5.Klinik für InnereMedizin d’Charité104 BerlinGermany
  6. 6.III BelklinikaSemmelweis Orvostudomanyi EgyetemBudapestHungary
  7. 7.Dept. of Pediatrics IISemmelweis Univ. Medical SchoolBudapestHungary
  8. 8.Dept. of PathologyMed. Univ. of PecsPecsHungary
  9. 9.Univ. KinderklinikJenaGermany

Personalised recommendations