Abstract
In the past 10 years the involvement of the central nervous system (CNS) in non- Hodgkin’s lymphomas (NHL) has become apparent as the results of systemic chemotherapy have improved and complete remissions (CR) have increased in both frequency and duration [3, 7]. However, most studies report on cases in which CNS lymphomas were identified through the recognition of neurological symptoms and cytological examination of cerebrospinal fluid (CSF). In some cases, there are only a few malignant lymphoma cells in the CSF of asymptomatic patients at diagnosis, and they are of uncertain clinical importance.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Andreef M (1980) Computer analysis of DNA histograms. University of Utrecht, p 36 (doctorate thesis)
Barligie B, Spitzer G, Hart JS, Johnson DA, Büchner T, Schumann J, Drewinko B (1976) DNA histogram analysis of human hemopoietic cells. Blood 48: 245–258
Ersbol I, Schultz HB, Thomsen BLR, Keiding N, Nissen N (1985) Meningeal involvement in non-Hodgkin’s lymphomas, incidence, risk factors and treatment. Scand J Haematol 36: 487–497
Glass JP, Melamed M, Chernik NL, Posner JB (1979) Malignant cells in cerebrospinal fluid (CSF). The meaning of a positive CSF cytology. Neurology 29: 1369–1375
Hansen M, Brynskov J, Christensen PA, Krinbel JJ, Gimsing P (1985) Cobalamin binding proteins (haptocornin and transcobalamin) in human cerebrospinal fluid. Scand J Haematol 34: 209–212
Konopka L, Pawelski S, Brodzki M, Wegier-Filipiuk B (1987) Cerebrospinal fluid vitamin B12 concentration and its binding capacity in acute leukemias. Fourth international symposium on Therapy of Acute Leukemias, Rome, Feb 7–12 (program and abstr)
Recht L, Straus DJ, Cirrincione C, Tzvi Thaler H, Posner JB (1987) Central nervous system metastases from non-Hodgkin’s lymphoma: treatment and prophylaxis. Am J Med 84: 425–435
Retief FP, Gottlieb CW, Herbert V (1967) Delivery of Co57B12 to erythrocytes from alpha and beta globulin of normal B12-deficient and chronic myeloid leukemia serum. Blood 29: 837–851
Swencz-Szczepanik K (1982) Examination of DNA content in leukemia cells of cerebrospinal fluid. Doctoral dissertation. Institute of Haematology, Warsaw
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Swencz-Szczepanik, K., Krämer, M., Konopka, L., Brodzki, M., Pawelski, S., Deptala, A. (1989). Central Nervous System Involvement in Non-Hodgkin’s Lymphomas. In: Neth, R., et al. Modern Trends in Human Leukemia VIII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74621-5_12
Download citation
DOI: https://doi.org/10.1007/978-3-642-74621-5_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-50967-7
Online ISBN: 978-3-642-74621-5
eBook Packages: Springer Book Archive