Abstract
Perifollicular nerve endings have been recognized for a long time, either by silver impregnation methods (Szymonowicz 1909; Weddell et al. 1955; Winkelmann 1959; Miller et al. 1960; Straile 1960; Seto 1963; Montagna et al. 1964; Mann 1968) or by histochemical techniques (Winkelmann 1968; Montagna and Parakkal 1974). These light microscopic studies revealed that human hairs, particularly vellus hairs, are richly endowed with networks of nerves. It was also found that the heaviest concentration of the nerve network encircles the follicle at the level of the sebaceous gland (Figs. 1–3).
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References
Andres KH (1966) Über die Feinstruktur der Rezeptoren an Sinushaaren. Z Zellforsch 75:339— 365
Aso M, Hashimoto K, Hamzavi A (1985) Immunohistochemical studies on selected skin diseases and tumors using monoclonal antibodies to neurofilament and myelin proteins (monoclonal antineural antibodies). J Am Acad Dermatol 13:37–42
Bloom W, Fawcett DW (1975) Blood and lymph vascular systems. In: Bloom W, Fawcett DW (eds) A textbook of histology, 10th edn. Saunders, Philadelphia, pp 372–395
Braverman IM, Sibley J, Keh-Yen A (1986) A study of the veil cells around normal, diabetic, and aged cutaneous micro vessels. J Invest Dermatol 86:57–62
Ellis RA (1961) Vascular patterns of the skin. In: Montagna WM, Ellis RA (eds) Blood vessels and circulation, vol 2. Pergamon, New York, pp 20–37
Garrett MH, Hashimoto K (1977) The pilary end-organ of quiescent facial vellus hair follicles in the mouse. J Tenn Acad Sci 52:140–147
Hashimoto K (1973a) Fine structure of perifollicular nerve endings in human hair. J Invest Dermatol 59:432–441
Hashimoto K (1973b) Fine structure of the Meissner corpuscle of human palmar skin. J Invest Dermatol 60:20–28
Hashimoto K (1978 a) Ultrastructure of human eccrine glands. In: Jarrett A (ed) Physiology and pathophysiology of the skin, vol 5. Academic, New York, pp 1543–1573
Hashimoto K (1978 b) Ultrastructure of human apocrine glands. In: Jarrett A (ed) Physiology and pathophysiology of the skin, vol 5. Academic, New York, pp 1575–1596
Hashimoto K, Lever WF (1970) An ultrastructural study of cell junctions in pemphigus vulgaris. Arch Dermatol 101:287–298
Ishibashi Y, Tsuru N (1976) Innervation of human hair follicles. In: Toda K, Ishibashi Y, Hari Y, Morikawa F (eds) Biology and diseases of the hair. University of Tokyo Press, Tokyo, pp 73–85
Kobayasi T (1974) An electron microscope study on the dermo-epidermal junction. Acta Derm Venereol (Stockh) 41:481–491
Mahrle G, Orfanos CE (1974) Merkel cells as human cutaneous neuro-receptor cells. Arch Dermatol Forsch 251:19–26
Mann SJ (1968) The tylotrich (hair) follicle of the American opossum. Anat Ree 160:171–180
Miller MR, Ralton HJ, Kasahara M (1960) The pattern of cutaneous innervation of the human hand, foot and breast. In: Montagna W (ed) Cutaneous innervation. Pergamon, Oxford, pp 1–47 (Advances in biology of skin, vol 1)
Montagna W, Parakkal PF (1974) The structure and function of skin, 3rd edn. Academic, New York
Montagna W, Yun J, Formisano V (1964) Histology and cytochemistry of human skin. XXX. Cholinesterase-containing nerves in face. Arch Dermatol 90:526–529
Orfanos C (1967) Elektronenmikroskopischer Nachweis epithelioneuraler Verbindungen (Mechano-Receptoren) am Haarfollikelepithel des Menschen. Arch Klin Exp Dermatol 228:421–429
Orfanos C (1968) Elektronenmikroskopische Befunde an den peritrichialen Nervenfasern des menschlichen Haarfollikels. In: Proceedings of 13th International Congress on Dermatology. Springer, New York, p 799
Parakkal PF (1966) The fine structure of the dermal papilla in the guinea pig hair follicle. J Ultrastruct Res 14:133–142
Schwartz DE, Paller AS, Lizak PP, Pearson RW (1986) Elastase and neutral cathepsin production by human fibroblasts: effect of culture conditions on synthesis and secretion. J Invest Dermatol 86:63–68
Seto H (1963) Studies on the sensory innervation (human sensibility) 2nd edn. Thomas, Springfield, pp 341–347
Stephens RJ, Beebe I J, Poulter TC (1973) Innervation of the vibrissae of the California sea lion. Anat Ree 176:421–442
Straile WE (1960) Sensory hair follicles in mammalian skin: the tylotrich follicle. Am J Anat 106:133–147
Szymonowicz L (1909) Über die Nervendigungen in den Haaren des Menschen. Arch Mikrosk Anat 74:622–635
Weddell G, Palmer E, Pallie W (1955) Nerve endings in mammalian skin. Biol Rev 30:159–195
Winkelmann RK (1959) The innervation of a hair follicle. Ann NY Acad Sci 83:400–407
Winkelmann RK (1968) New methods for the study of nerve endings. In: Kenshalo DR (ed) The skin senses. Thomas, Springfield, pp 38–60
Yamamoto T (1966) On the sensory innervation of the hair follicle in mice. In: Proceedings of 6th International Congress Electron Microscopy, Tokyo. Maruzen Asia, Singapore, pp 515–516
Sato S, Nishijima A, Hiraga K (1976) Changes in basal lamina of blood vessels within hair dermal papilla: a possible relation to the hair cycle. In: Toda K, Ishibashi Y, Hori Y, Morikawa F, Kobori T, Montagna W (eds) Biology and diseases of the hair. University of Tokyo Press, Tokyo, pp 87–102
Suzuki Y, Hashimoto K (1986) The value of blood group specific lectins and endothelial associated antibodies in the diagnosis of vascular proliferations. J Cutan Pathol (to be published)
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Hashimoto, K., Ito, M., Suzuki, Y. (1990). Innervation and Vasculature of the Hair Follicle. In: Orfanos, C.E., Happle, R. (eds) Hair and Hair Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74612-3_6
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DOI: https://doi.org/10.1007/978-3-642-74612-3_6
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