The Biological Activity of Early SV40 Antisense RNA and DNA Molecules

Graessmann, M.; Graessmann, A.

doi:10.1007/978-3-642-74578-2_12

The Biological Activity of Early SV40 Antisense RNA and DNA Molecules

M. Graessmann¹³ &
A. Graessmann¹³

Conference paper

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 144))

Abstract

It is of basic and applied scientific interest to develop reliable techniques which allow the down regulation of single genes either in isolated cells or in cells of an intact organism. Such an approach should give us a more detailed insight into the particular role of single genes for growth and cell differentiation and offer us the possibility to cure cells in cases in which overproduction of a specific protein is the reason for the cellular malfunction. One promising method to decrease selectively the expression rate of either endogeneous or transgenes at the post-transcriptional level is the use of antisense RNA and DNA molecules.

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References

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Authors and Affiliations

Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Arnimallee 22, 1000, Berlin 33, Germany
M. Graessmann & A. Graessmann

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M. Graessmann
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A. Graessmann
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Editors and Affiliations

Fakultät für Biologie, Universität Konstanz, D-7750, Konstanz, Germany
Rolf Knippers Dr.
Department of Biology, Princeton University, Princeton, N.J., 08544-1014, USA
Arnold J. Levine Ph.D.

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Graessmann, M., Graessmann, A. (1989). The Biological Activity of Early SV40 Antisense RNA and DNA Molecules. In: Knippers, R., Levine, A.J. (eds) Transforming Proteins of DNA Tumor Viruses. Current Topics in Microbiology and Immunology, vol 144. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74578-2_12

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DOI: https://doi.org/10.1007/978-3-642-74578-2_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-74580-5
Online ISBN: 978-3-642-74578-2
eBook Packages: Springer Book Archive

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