Epileptic Phenomena in the Neocortex: From Activity of Single Neurons to Field Potentials of Neuronal Pools
In the past epileptic phenomena have been identified by such terms as “hyperexcitation” or “hypersynchronization.” These terms, which are merely descriptive, come from studies of EEG phenomena such as spikes, sharp waves, and spike-wave complexes. As these electrographic features (graphoelements) imply overwhelming excitatory processes, one was inclined to think of an epileptic focus as an aggregate of neurons totally in a state of excitation and virtually devoid of inhibition.
KeywordsSingle Neuron Cortical Layer Cortical Surface Epileptic Activity Epileptic Focus
Unable to display preview. Download preview PDF.
- Petsche H, Pockberger H, Rappelsberger P (1987) Mechanisms leading to the propagation of self-sustained seizure activities. In: Wieser HG, Speckmann E-J, Engel J (eds) The epileptic focus. John Libbey Eurotext, London, pp 59–81Google Scholar
- Prince DA, Wilder BJ (1967) Control mechanisms in cortical epileptogenic foci. Arch Neurol Psychiatry 16: 194–202Google Scholar
- Speckmann E-J (1986) Experimentelle Epilepsieforschung. Wissenschaftliche Buchgesellschaft, DarmstadtGoogle Scholar
- Speckmann E-J, Witte OW, Walden J (1986) Involvement of calcium ions in focal epileptic activity of the neocortex. In: Heinemann U, Klee M, Neher E, Singer W (eds) Calcium electrogenesis and neuronal functioning. Springer, Berlin Heidelberg New York, pp 386–395 (Experimental Brain Research Series, vol 14 )Google Scholar