Biosynthesis of Tropane Alkaloids

  • Y. Yamada
  • T. Hashimoto
  • T. Endo


As with other secondary products, the biosynthesis of tropane alkaloids in plants has been extensively investigated by the use of labelled precursors (for a review, see [11]). Recent advances in the techniques of alkaloid analysis and enzyme purification, however, have now made it possible to isolate and characterize biosynthetic enzymes in the pathway, and earlier results using precursor feeding must be validated and may necessitate a revision of the biosynthetic pathways proposed. A prerequisite to such studies is a sufficient supply of cell material with high biosynthetic capability, thus, with high enzyme activities.


Root Culture Somatic Hybrid Mesophyll Protoplast Tropane Alkaloid Hydroxyl Oxygen 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • Y. Yamada
  • T. Hashimoto
  • T. Endo
    • 1
  1. 1.Research Center for Cell and Tissue Culture, Faculty of AgricultureKyoto UniversitySakyo-ku, Kyoto 606Japan

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