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Oral Immunization Against Cholera

  • Conference paper
New Strategies for Oral Immunization

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 146))

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Abstract

Cholera is an important cause of morbidity and mortality in many developing countries. Convalescents from this disease develop a substantial but not complete immunity against new attacks of cholera (Glass et al. 1982). Although cholera can be effectively treated by oral and/or intravenous rehydration, development of a vaccine that is capable of preventing cases and reducing the severity of cholera would provide the best immediate possibility to control the disease. If this vaccine could also provide protection against diarrhea caused by heat-labile enterotoxin (LT)-producing Escherichia coli its importance as a preventive health measure would be even more significant (Holmgren and Svennerholm 1985).

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References

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© 1989 Springer-Verlag Berlin · Heidelberg

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Holmgren, J., Clemens, J., Sack, D.A., Sanchez, J., Svennerholm, AM. (1989). Oral Immunization Against Cholera. In: Mestecky, J., McGhee, J.R. (eds) New Strategies for Oral Immunization. Current Topics in Microbiology and Immunology, vol 146. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74529-4_21

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  • DOI: https://doi.org/10.1007/978-3-642-74529-4_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74531-7

  • Online ISBN: 978-3-642-74529-4

  • eBook Packages: Springer Book Archive

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