Autoradiographic Study of Oxalate in Rats

  • T. Sugimoto
  • H. Osswald
  • T. Kishimoto
  • K. Yamamoto
  • T. Kanazawa
  • H. Rübben
  • T. Matsumura
Conference paper

Abstract

We have already reported pharmacokinetic studies of oxalate in rats using radio-isotopes; oxalate is more diffusible through biological membranes than inulin, and oxalate is excreted mainly by the kidney, although some is excreted by the liver (Sugimoto et al. 1988). Here, we checked these results in an autoradiographic study of oxalate in rats. Autoradiograms made after an injection of [14C]oxalate were com-pared with those made after an injection of [14C]inulin.

Keywords

Cellulose Acetone Carboxyl Oxalate Inulin 

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References

  1. Banwart C, Hagmaier V, Rutishauser G, Sieler H (1979) Absorption of oxalic acid in rats by means of a 14C method. Eur Urol 5: 276–277Google Scholar
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • T. Sugimoto
    • 1
  • H. Osswald
    • 2
  • T. Kishimoto
    • 1
  • K. Yamamoto
    • 1
  • T. Kanazawa
    • 1
  • H. Rübben
    • 2
  • T. Matsumura
    • 1
  1. 1.Department of UrologyOsaka City University Medical SchoolOsakaJapan
  2. 2.Department of Urology and PharmacologyRWTH-AachenAachenGermany

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