Autoradiographic Study of Oxalate in Rats
We have already reported pharmacokinetic studies of oxalate in rats using radio-isotopes; oxalate is more diffusible through biological membranes than inulin, and oxalate is excreted mainly by the kidney, although some is excreted by the liver (Sugimoto et al. 1988). Here, we checked these results in an autoradiographic study of oxalate in rats. Autoradiograms made after an injection of [14C]oxalate were com-pared with those made after an injection of [14C]inulin.
KeywordsSmall Intestine Oxalic Acid Pharmacokinetic Study Methyl Cellulose Autoradiographic Study
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