Age-Dependency and Regional Distribution of Enkephalinergic Nerves in the Human Prostate

  • T. Jungblut
  • G. Aumüller
  • B. Malek
  • H. Melchior
Conference paper


Numerous studies have been made of the autonomic innervation of the prostate in different mammals, including humans (e.g., Sjöstrand 1965; Norberg et al. 1967; Vaalasti and Hervonen 1979, 1980). These studies have revealed a dual adrenergic and cholinergic autonomic innervation of this organ. Since the first reports of the existence of enkephalin-immunoreactive nerves in the male urogenital tract (Vaalasti et al. 1980; Aim et al. 1981), the presence of these nerves has been confirmed (Del Fiacco 1982; Vaalasti et al. 1986). The enkephalins may act as neurotransmitters in concert with the classical transmitters (Burnstock 1986; Fried et al. 1986; De Potter et al. 1987). In spite of this, close to nothing is known about the histotopography, the chemical diversity, and the hormone sensitivity or age dependency of these peptidergic nerves.


Seminal Vesicle Human Prostate Regional Distribution Autonomic Innervation Ganglionic Cell 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • T. Jungblut
    • 1
  • G. Aumüller
    • 2
  • B. Malek
    • 3
  • H. Melchior
    • 1
  1. 1.Klinik für Urologieder Städtischen Kliniken KasselGermany
  2. 2.Institut für AnatomiePhilipps-Universität MarburgGermany
  3. 3.Klinik für DermatologieJustus-Liebig-Universität GießenGermany

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