Skip to main content

Selenium in the Central Nervous System of the Rat After Exposure to 75-Se-L-Selenomethionine

  • Conference paper
Selenium in Biology and Medicine

Abstract

The toxicity of selenium was well known long before selenium was established as an essential trace element to man and animals. Especially the central nervous system seems to be sensitive to this toxicity, since neurological symptoms like ataxia, motor incoordination, hyperreflexia, paralysis, depression, anorexia and lack of vitality are outstanding symptoms in animals exposed to toxic amounts of selenium (Moxon 1937).

To whom all correspondence should be addressed

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Ammar EM, Couri D (1981) Acute toxicity of sodium selenite and selenomethionine in mice after ICV or IV administration. Neurotoxicology 2: 383–386

    PubMed  CAS  Google Scholar 

  • Beilstein MA, Whanger PD (1986) Chemical forms of selenium in rat tissues after administration of selenite and selenomethionine. J Nutr 116: 1711–1719

    PubMed  CAS  Google Scholar 

  • Brown DG, Burk RF (1973) Selenium in tissues and sperm of rats fed a torula yeast diet. J Nutr 102: 102–108

    Google Scholar 

  • Moxon AL (1937) Alkali disease or selenium poisoning. S D Agric Exp Stn Bull 311: 1–91

    Google Scholar 

  • Prohaska JR, Ganther HE (1976) Selenium and glutathione peroxidase in developing rat brain. J Neurochem 27: 1379–1387

    Article  PubMed  CAS  Google Scholar 

  • Trapp GA, Millam J (1974) The distribution of 75-Se in brains of selenium deficient rats. J Neurochem 24: 593–595

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Grøbæk, H., Thorlacius-Ussing, O. (1989). Selenium in the Central Nervous System of the Rat After Exposure to 75-Se-L-Selenomethionine. In: Wendel, A. (eds) Selenium in Biology and Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74421-1_26

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-74421-1_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74423-5

  • Online ISBN: 978-3-642-74421-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics