Skip to main content
SpringerLink
Log in

The Serum Gamma-glutamyltransferase Isoenzyme System and its Diagnostic Role in Hepatobiliary Diseases

  • Conference paper
Clinical Biochemistry in Hepatobiliary Diseases

Part of the book series: Progress in Clinical Biochemistry and Medicine ((PCBM,volume 8))

Abstract

In this review some novel methodological and clinical aspects of human serum gamma-glutamyl-transferase (GGT; E.C. 2.3.2.2) are presented and discussed within the framework of a general survey on the enzyme.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Szczeklik E, Orlowski M, Szewcsuk A (1961) Gastroenterol 41: 353

    Google Scholar 

  2. Goldberg DM (1979) Lab 6: 5

    CAS  Google Scholar 

  3. Hardison WGM (1979) in: Griffiths JC (ed) Clinical Enzymology: Gamma-glutamyltranspeptidase: A clinical overview. Masson, New York, p 199

    Google Scholar 

  4. Goldberg DM (1980) Crit Rev Clin Lab Sci 12: 1

    Article  CAS  Google Scholar 

  5. Penn R, Worthington D (1983) Br Med J 286: 531

    Article  CAS  Google Scholar 

  6. Nemesànszky E, Lott A (1985) Clin Chem 31: 797

    PubMed  Google Scholar 

  7. Meister A, Tate SS, Ross LL (1976) in : Martonosi A (ed) The enzymes of biological membranes. Plenum Press, New York p 315

    Google Scholar 

  8. Tate SS, Meister A (1981) Mol Cell Biochem 39: 357

    Article  PubMed  CAS  Google Scholar 

  9. Meister A (1973) Science 180: 33

    Article  PubMed  CAS  Google Scholar 

  10. Curthoys NP, Shapiro R (1975) Febs Lett 58: 230

    Article  PubMed  CAS  Google Scholar 

  11. Binkley F, Wiesemann ML, Groth DP, Powell RW (1975) Febs lett 51: 168

    Article  PubMed  CAS  Google Scholar 

  12. Huseby NE (1978) Biochim Biophys Acta 522: 354

    PubMed  CAS  Google Scholar 

  13. Horchi S, Inoue M, Marino Y (1978) Eur J Biochem 87: 429

    Article  Google Scholar 

  14. Scherberich JE, Kíeemann B, Mondorf W (1979) Clin Chim Acta 93: 35

    Article  PubMed  CAS  Google Scholar 

  15. Masuike M, Ogawa M, Kosaki G, Minamuira N, Yamamoto T (1982) Enzyme 27: 163

    PubMed  CAS  Google Scholar 

  16. Lilja H, Weiber H (1985) Scand J Clin Lab Invest 43: 307

    Article  Google Scholar 

  17. Yamaguchi N (1985) Clin Chim Acta 147: 75

    Article  PubMed  CAS  Google Scholar 

  18. Tate SS, Khadse V, Wellner D (1988) Arch Biochem Biophys 262: 397

    Article  PubMed  CAS  Google Scholar 

  19. Braun JP, Tainturier D, Bezille P, Raviart I, Rico AG (1984) Enzyme 31: 193

    PubMed  CAS  Google Scholar 

  20. Sobiech KA, Wieczorek E (1981) Enzyme 26: 153

    PubMed  CAS  Google Scholar 

  21. Tate SS, Ross ME (1977) J Biol Chem 252: 6042

    PubMed  CAS  Google Scholar 

  22. Huseby NE (1977) Biochim Biophys Acta 483: 46

    PubMed  CAS  Google Scholar 

  23. Shaw LM, London JW, Petersen LE (1978) Clin Chem 24: 905

    PubMed  CAS  Google Scholar 

  24. Shaw LM, Petersen Archer L, London JW, Marsh E (1980) Clin Chem 26: 1523

    PubMed  CAS  Google Scholar 

  25. Sundarsingh Daniel D, Ramakrishna BS, Balasubramanian KA (1987) Clin Chim Acta 162: 319

    Article  Google Scholar 

  26. Goodman SI, Mace JW, Poliak S (1971) Lancet i: 234

    Article  Google Scholar 

  27. Schulman JD, Goodman SI, Mace JW, Patrick AD, Tietze F, Butler E (1975) Biochem Biophys Res Comm 65: 68

    Article  PubMed  CAS  Google Scholar 

  28. Rambabu K, Pattabiraman TN (1976) Clin Chim Acta 73: 251

    Article  PubMed  CAS  Google Scholar 

  29. Rambabu K, Jacob RT, Pattabiraman TN (1981) Clin Chim Acta 109: 257

    Article  PubMed  CAS  Google Scholar 

  30. Salgo L, Szabo A (1982) Clin Chim Acta 126: 9

    Article  PubMed  CAS  Google Scholar 

  31. Linder M, Sudaka P (1982) Clin Chim Acta 118: 77

    Article  PubMed  CAS  Google Scholar 

  32. Jung K, Wischke UW (1984) Clin Chem 30: 856

    PubMed  CAS  Google Scholar 

  33. Jung K, Pergande M, Reinholdt C, Schulze B, Scholz D, Strobelt V (1984) J Clin Chem Clin Biochem 22: 523

    PubMed  CAS  Google Scholar 

  34. Amodio P, Bazzerla G, Malatesta R, Gatta A (1985) Enzyme 33: 216

    PubMed  CAS  Google Scholar 

  35. Ruiz-Moral R, Perez-Jimenez F, Cosano A, Hens M, Munoz L, Jimenez Alonso J, Munoz R, Pereperez JJ (1985) Enzyme 33: 105

    PubMed  CAS  Google Scholar 

  36. Jimenez-Alonso J, Jaimez L, Perez-Jimenez F, Grilo A, Jimenez-Pereperez JA (1982) Clin Chem 28: 1988

    PubMed  CAS  Google Scholar 

  37. Wenham PR, Price CP, Sammons HG (1978) J Clin Pathol 31: 666

    Article  PubMed  CAS  Google Scholar 

  38. Indirani N, Hill PG (1977) Biochim Biophys Acta 483: 57

    PubMed  CAS  Google Scholar 

  39. Wenham PR, Horn DB, Smith AF (1981) Clin Chim Acta 112: 113

    Article  PubMed  CAS  Google Scholar 

  40. Bulle F, Mattei MG, Pawlak A, Passage E, Chobert MN, Laperche Y, Guellaen G (1987) Human Genet 76: 283

    Article  CAS  Google Scholar 

  41. Laperche Y, Bulle F, Aissani T, Chobert MN, Aggerbeck M, Hanoune J, Guellaen G (1986) Proc. Natl Acad Sci 83: 937

    Article  PubMed  CAS  Google Scholar 

  42. Coloma J, Pitot HC (1986) Nucl Acids Res 14: 1393

    Article  PubMed  CAS  Google Scholar 

  43. Tate SS, Nash B (1987) Febs Lett 211: 133

    Article  PubMed  CAS  Google Scholar 

  44. Tate SS, Meister A (1977) Proc Natl Acad Sci (USA) 74: 931

    Article  CAS  Google Scholar 

  45. Hornichi S, Inoue M, Morino Y (1978) Biochem Biophys Res Comm 80: 873

    Article  Google Scholar 

  46. Tate SS (1986) Febs Lett 194: 33

    Article  PubMed  CAS  Google Scholar 

  47. Nash B, Tate SS (1982) J Biol Chem 257–585

    Google Scholar 

  48. Nash B, Tate SS (1984) J Biol Chem 259–678

    Google Scholar 

  49. Matsuda Y, Tsuji A, Kuno T, Katunuma N (1983) J Biochem 94: 755

    PubMed  CAS  Google Scholar 

  50. Altman RA, Hughey RP (1986) Biochem Intern 13: 1009

    CAS  Google Scholar 

  51. Matsuda Y, Tsuji A, Katunuma N (1983) J Biochem 93: 1427

    PubMed  CAS  Google Scholar 

  52. Miura T, Matsuda Y, Tsuji A, Katunuma N (1981) J Biochem 89: 217

    PubMed  CAS  Google Scholar 

  53. Tsuchida S, Imai F, Sato K (1981) J Biochem 89: 775

    PubMed  CAS  Google Scholar 

  54. Das ND, Shichi H (1979) Life Sci 25: 1821

    Article  PubMed  CAS  Google Scholar 

  55. Huseby NE (1982) Clin Chim Acta 124: 103

    Article  PubMed  CAS  Google Scholar 

  56. Wenham PR, Horn DB, Smith AF (1985) Clin Chem 31: 569

    PubMed  CAS  Google Scholar 

  57. Huseby NE (1986) Adv Clin Enzymol 3: 67

    CAS  Google Scholar 

  58. Wenham PR (1986) Adv Clin Enzymol 3: 74

    CAS  Google Scholar 

  59. Artur Y, Sanderink GJ, Maire J (1987) Ann Biol Clin 45: 277

    CAS  Google Scholar 

  60. Castaldo G, Fortunato G, Salvatore F, Sacchetti L (1988) It J Biochem 37: 111

    CAS  Google Scholar 

  61. Artur Y, Wellman-Bednawska M, Jacquier A, Siest G (1984) Clin Chem 30: 631

    PubMed  CAS  Google Scholar 

  62. Artur Y, Wellman-Bednawska M, Jacquier A, Siest G (1984) Clin Chem 30: 1318

    PubMed  CAS  Google Scholar 

  63. De Broe ME, Borgers M, Wieme RJ (1975) Clin Chem Acta 59: 369

    Article  Google Scholar 

  64. Moss DW (1984) in: Goldberg DM, Werner M (eds) Selected Topics in Clin Enzymol 2: 517

    Google Scholar 

  65. Moss DW, Echetebu ZO, Whitaker KB, Traynor OJ, Wood CB (1982) in: Siest G, Heusghem C (eds) Gamma-glutamyltransferases. Adv Biochem Pharmacol 3rd series, p 41

    Google Scholar 

  66. Echetebu ZO, Moss DW (1982) Enzyme 27: 1

    PubMed  CAS  Google Scholar 

  67. Echetebu ZO, Moss DW (1982) Enzyme 27: 9

    PubMed  CAS  Google Scholar 

  68. Ishii H, Yasuraoka S, Shigeta Y, Takagi S, Kamiya T, Okuno F, Miyamoto K, Tsuchiya M (1978) Life Sci 23: 1393

    Article  PubMed  CAS  Google Scholar 

  69. Homer F, Kellen JA, Kingstone E, Maharaj N, Malkin A (1979) Enzyme 24: 217

    Google Scholar 

  70. Kok PJMJ, Seidel B, Holtkamp HC, Huisman J (1978) Clin Chim Acta 90: 209

    Article  PubMed  CAS  Google Scholar 

  71. Braide SA, Davies TJ (1987) Ann Clin Biochem 24: 391

    PubMed  Google Scholar 

  72. Artur Y, Wellman-Bednawska M, Siest G (1984) Ann Biol Clin 42: 115

    CAS  Google Scholar 

  73. Bornschein W (1975) Clin Chim Acta 61: 325

    Article  PubMed  CAS  Google Scholar 

  74. Laursen T, Jacyszyn K (1968) Clin Chim Acta 21: 497

    Article  PubMed  CAS  Google Scholar 

  75. Burlina A (1978) Clin Chem 24: 502

    PubMed  CAS  Google Scholar 

  76. Rosalki SB, Nemesànszky E, Foo A Y (1981) Ann Clin Biochem 18: 25

    PubMed  CAS  Google Scholar 

  77. Park HR, Geitner AM, Fritsche HA (1984) Clin Chem 30: 1010

    Google Scholar 

  78. Hammond KD, Gravenor MJ, Piesas D (1985) Ann Clin Biochem 22: 376

    PubMed  Google Scholar 

  79. Burlina A, Secchiero S, Bertorelle R, Zaninotto M (1987) Med Sci Res 15: 499

    CAS  Google Scholar 

  80. Hetland O, Andersson TR, Gerner T (1975) Clin Chim Acta 62: 425

    Article  PubMed  CAS  Google Scholar 

  81. Echetebu ZO, Moss DW (1979) Clin Chim Acta 95: 433

    Article  PubMed  CAS  Google Scholar 

  82. Wenham PR, Price CP, Sammons HG (1978) Ann Clin Biochem 15: 146

    PubMed  CAS  Google Scholar 

  83. Koima J, Kanatani M, Nakamura N, Kashiwagi T, Tohjoh F, Akiyama M (1980) Clin Chim Acta 106: 165

    Article  Google Scholar 

  84. Sawabu N, Nakagen M, Ozaki K, Wbkabayashi T, Toya D, Hattori N, Ishii M (1983) Cancer 51: 327

    Article  PubMed  CAS  Google Scholar 

  85. Kew MC, Wolf P, Whittaker D, Rowe P (1984) Br J Cancer 50: 451

    Article  PubMed  CAS  Google Scholar 

  86. Sinha PK, Righetti PG (1986) J Biochem Biophys Meth 12: 289

    Article  PubMed  CAS  Google Scholar 

  87. Sinha P, Kottgen E, Righetti PG (1988) Fres Z Anal Chem 8216: 1

    Google Scholar 

  88. Lilja H, Jeppsson JO, Kristensson H (1983) Clin Chem 29: 1034

    PubMed  CAS  Google Scholar 

  89. Delanghe J, Buyzere M, Faust U, Krause-Jarres J, De Scheerder I (1987) Enzyme 83: 22

    Google Scholar 

  90. Delanghe JR, Buyzere ML, De Scheerder IK, Claeys LR, Wieme RJ (1987) Clin Chim Acta 162: 311

    Article  PubMed  CAS  Google Scholar 

  91. Tsuji A, Matsuda Y, Katunuma N (1980) Clin Chim Acta 104: 361

    Article  PubMed  CAS  Google Scholar 

  92. Hoskins JA, Davies FF (1986) Anal Biochem 152: 314

    Article  PubMed  CAS  Google Scholar 

  93. Sacchetti L, Castaldo G, Fortunato G, Salvatore F (1988) Clin Chem 34: 419

    PubMed  CAS  Google Scholar 

  94. Sacchetti L, Castaldo G, Salvatore F (1988) Clin Chem 34: 352

    PubMed  CAS  Google Scholar 

  95. Rosalki SB (1982) in: Siest G, Heusghem C (eds) Gamma-glutamyltransferases. Adv Biochem Pharmacol 3rd series, p 147

    Google Scholar 

  96. Brocklenurst D, Wilde CE (1980) Clin Chem 26: 588

    Google Scholar 

  97. Buamah PK, Skillen AW, Davison V (1984) Clin Chim Acta 141: 285

    Article  Google Scholar 

  98. Carbarns NJ, Gasden C, Brock DJH (1983) Lancet i: 329

    Article  Google Scholar 

  99. Jalanko H, Ranta T, Lehtonem E, Roaslahti E (1983) Clin Chim Acta 134: 337

    Article  PubMed  CAS  Google Scholar 

  100. Moniz C, Nicolaides KH, Keys D, Rodeck CH (1984) J Clin Pathol 37: 700

    Article  PubMed  CAS  Google Scholar 

  101. Garcia MP, Tutor JC, Sanjose M, Porto JA, Fraga JM, Paz JM, Rodriguez-Segade S (1987) Clin Biochem 20: 269

    Article  PubMed  CAS  Google Scholar 

  102. Galen RS, Gambino SR (1976) in: Galen SR, Gambino SR (eds) Beyond normality: the predictive value and efficiency of medical diagnoses, Wiley and Sons, New York

    Google Scholar 

  103. Rosalki SB, Foo AY, Hjelm M, Dinwiddie R (1985) Clin Chem 31: 779

    PubMed  CAS  Google Scholar 

  104. Huseby NE, Eide TJ (1983) Clin Chim Acta 135: 301

    Article  PubMed  CAS  Google Scholar 

  105. Yamaguchi N, Kawai K, Ashihara T (1986) Clin Chim Acta 154: 133

    Article  PubMed  CAS  Google Scholar 

  106. Yamamoto H, Sumikawa K, Hada T, Higashino K, Yamamura Y (1981) Clin Chim Acta 111: 229

    Article  PubMed  CAS  Google Scholar 

  107. Tsuchida S, Yamazaki T, Cambo EM, Morita T, Matsue H, Yoshida Y, Sato K (1985) Clin Chim Acta 152: 17

    Article  PubMed  CAS  Google Scholar 

  108. Taniguchi N, House S, Kuzumaki N, Yokosawa N, Yamagiwa S, Lizuka S, Makita A, Sekiya C (1985) J Natl Cancer Inst 75: 841

    PubMed  CAS  Google Scholar 

  109. Taniguchi N, Lizuka S, Nai Zhe Z, Honse S, Yokosawa N, Ono M, Kinoshita K, Makita A, Sekiya C (1985) Cancer Res 45: 5835

    PubMed  CAS  Google Scholar 

  110. Chin HP, Scholnick HR, Morfìn R (1970) J Lipid Res 11: 583

    Google Scholar 

  111. Sacchetti L, Castaldo G, Cimino L, Budillon G, Salvatore F (1988) Clin Chim Acta 177: 167

    Article  PubMed  CAS  Google Scholar 

  112. Pawlak A, Lahuna O, Bulle F, Suzuki A, Ferry N, Siegrist S, Chikhi N, Chobert MN, Guellaen G, Laperche Y (1988) J Biol Chem 263: 9913

    PubMed  CAS  Google Scholar 

  113. Rajpert-De Meyts E, Heisterkamp N, Groffen J (1988) Proc Natl Acad Sci USA 85: 8840

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dipartimento di Biochimica e Biotecnologie Mediche, II Facoltà di Medicina, Università di Napoli, via S. Pansini 5, I-80131, Napoli, Italy

    Lucia Sacchetti, Giuseppe Castaldo & Francesco Salvatore

Authors
  1. Lucia Sacchetti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Giuseppe Castaldo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Francesco Salvatore
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Dipartimento di Biochimica e Biotecnologie Mediche, II Facoltà di Medicina, Università di Napoli, Via S. Pansini, 5, I-80131, Napoli, Italy

    Francesco Salvatore  & Lucia Sacchetti  & 

  2. Istituto di Chimica Analitica, Università di Messina, Italy

    Aldo Roda

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Sacchetti, L., Castaldo, G., Salvatore, F. (1989). The Serum Gamma-glutamyltransferase Isoenzyme System and its Diagnostic Role in Hepatobiliary Diseases. In: Salvatore, F., Roda, A., Sacchetti, L. (eds) Clinical Biochemistry in Hepatobiliary Diseases. Progress in Clinical Biochemistry and Medicine, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74394-8_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-74394-8_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74396-2

  • Online ISBN: 978-3-642-74394-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation