Skip to main content
  • 54 Accesses

Zusammenfassung

Die Schwangerschaft ist durch einen Abfall des peripheren Widerstands gekennzeichnet. In Anlehnung an das Ohmsche Gesetz wird der Widerstand im Kreislaufsystem aus Herzzeitvolumen und mittlerem arteriellem Blutdruck berechnet. Unberührt von dieser Überlegung blieb lange Zeit die rheologische Komponente, die vor allem im venösen Teil der Zirkulation Bedeutung erlangt.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Assali NS, Vaugh DL (1977) Blood volume in pre–eclampsia: fantasy and reality. Am J Obstet Gynecol 129: 355

    PubMed  CAS  Google Scholar 

  2. Benedetti TJ, Cotton DB, Miller RJC (1980) Hemodynamic Observation in severe preeclampsia with a flow directed pulmonary catheter. Am J Obstet Gynecol 136: 465

    PubMed  CAS  Google Scholar 

  3. Blaustein MP (1977) Sodium ions, calcium ions, blood pressure regulation and hypertension: a reassessement and a hypothesis. Am J Physiol 232:C 165

    Google Scholar 

  4. Buchan PC (1980) Evaluation and modification of whole blood filtration in the measurement of erythrocyte deformability in pregnancy and the newborn. Br J Haematol 45: 97–105

    Article  PubMed  CAS  Google Scholar 

  5. Buchan PC (1984) Fetal intrauterine redartation and hyperviscosity. In: Heilmann L, Buchan PC (eds) Hemorheological disorders in obstetrics and neonatology. Schattauer, Stuttgart

    Google Scholar 

  6. Buchan PC (1984) Maternal and fetal blood viscosity throughout normal pregnancy. J Obstet 4: 143–150

    Article  Google Scholar 

  7. Chesley LC (1972) Plasma and red cell volumes during pregnancy. Am J Obstet Gynecol 112: 440

    PubMed  CAS  Google Scholar 

  8. Chien S (1972) Present state of blood rheology. In: Messmer K, Schmid–Schönbein H (eds) Hemodilution. Theoretical basis and clinical application. Karger, Basel

    Google Scholar 

  9. Clark SL, Horeustein JM, Phlean JP, Montay TW, Paul RH (1985) Experience with the pulmonary artery catheter in obstetrics and gynecology. Am J Obstet Gynecol 152: 371–378

    Google Scholar 

  10. Cotton DB, Gonik G, Dorman KF (1985) Cardiovascular alterations in severe pregnancy induced hypertension seen with an intravenous given hydralazine bolus. Surg Gynecol Obstet 161: 240–245

    PubMed  CAS  Google Scholar 

  11. Cunningham FG, Lowe T, Guss S, Mason R (1985) Erythrocyte morphology in women with severe pre–eclampsia and eclampsia. Am J Obstet Gynecol 153: 318

    Google Scholar 

  12. Cusson J, Gutkowska J, Rey E, Michon N, Buocher M, Larochelle (1985) Plasma concentration of atrial natriuretic factor in normal pregnancy. N Engl J Med 313: 1230

    Google Scholar 

  13. Dintenfass L (1982) On changes in aggregation of red cells, blood viscosity and plasma viscosity during normal gestation. Clin Hemorheol 2: 175–188

    Google Scholar 

  14. Durocher JR, Weir EG, Lundblad WE, Patow M, Conrad E (1975) Effect of oral contraceptives and pregnancy on erythrocyte deformability and surface charge. Proc Soc Exp Biol Med 150: 368–370

    PubMed  CAS  Google Scholar 

  15. Foley ME, Isherwood DM (1978) Viscosity, hematocrit, fibrinogen and plasma proteins in maternal and cord blood. Br J Obstet Gynaecol 85: 500–504

    Article  PubMed  CAS  Google Scholar 

  16. Gallery EDM, Hunyor SN, Györy AZ (1979) Plasma volume contraction: a significant factor in both pregnancy–associated hypertension (pre–eclampsia) and chronic hypertension in

    Google Scholar 

  17. pregnancy. Q J Med 48:591

    Google Scholar 

  18. Gallery EDM, Delprado W, Györy AZ (1981) Antihypertensive effect of plasma volume expansion in pregnancy–associated hypertension. Aust NZJ Med 11: 20

    CAS  Google Scholar 

  19. Gant NF, Daley GL, Chand S, Whalley, Mac Donal PC (1973) A study of angiotensin II pressor response throughout primigravid pregnancy. J Clin Invest 52: 2682

    Article  PubMed  CAS  Google Scholar 

  20. Garn SM, Ridella SA, Petzold AS, Falkner F (1981) Maternal hematologic levels and pregnancy outcomes. Semin Perinatol 5: 155

    PubMed  CAS  Google Scholar 

  21. Giles WB, Lingman G, Marsal K, Trudinger BJ (1986) Fetal volume blood flow and umbilical artery flow velocity wave form analysis: a comparison. Br J Obstet Gynecol 93: 461–165

    CAS  Google Scholar 

  22. Giles WB, Trudinger BJ, Palmer AA (1986) Umbilical cord whole blood viscosity and the umbilical flow velocity time waveforms a correlation. Br J Obstet Gynaecol 93: 466–470

    PubMed  CAS  Google Scholar 

  23. Goodlin RC, Cotton DB, Haesslein HC (1978) Severe edema–proteinuria–hypertension gestosis. Am J Obstet Gynecol 132: 595

    PubMed  CAS  Google Scholar 

  24. Goodlin RC, Holdt D, Woods R (1982) Pregnancy–induced hypertension with hypervolemia. Case report. Am J Obstet Gynecol 142: 114

    Google Scholar 

  25. Goodlin RC (1982) Why treat the physiologic anemias of pregnancy. J Reprod Med 27: 639–646

    PubMed  CAS  Google Scholar 

  26. Goodlin RC, Dobry CA, Anderson JC (1983) Clinical signs of normal plasma volume expansion during pregnancy. Am J Obstet Gynecol 145: 1001

    PubMed  CAS  Google Scholar 

  27. Goodlin RC, Quaff MA, Smith JJ (1983) Hypovolemic pregnant women and their risk determinants. Int J Gynecol Obstet 21: 45–50

    Article  CAS  Google Scholar 

  28. Goodlin RC (1983) The importance of plasma volume expansion to normal pregnancy. In: Lauersen NH (ed) Modern management of high risk pregnancy. Plenum Med, New York

    Google Scholar 

  29. Goodlin RC, Wodds R, Mc Kinney ME, Hofschire PJ, Russel–Churchill GA (1985) Elevated static pressure and pregnancy well being. Am J Obstet Gynecol 152: 462–466

    PubMed  CAS  Google Scholar 

  30. Goodlin RC (1986) Expanded toxemia syndrome or gestosis. Am J Obstet Gynecol 154: 1227–1233

    PubMed  CAS  Google Scholar 

  31. Groenendijk R, Trimbos JBJ, Wallenburg HCS (1984) Hemodynamic measurement in preeclampsia: preliminary observation. Am J Obstet Gynecol 149: 232–236

    Google Scholar 

  32. Guyton AC (1963) Circulatory physiology: cardiac output and its regulation. Saunders, Philadelphia

    Google Scholar 

  33. Hamilton HFH (1950) Blood viscosity in pregnancy. J Obstet Gynaecol Br Commonw 57: 530–538

    Article  CAS  Google Scholar 

  34. Hankins GD, Wendel GD, Cunningham FG, Leveno KJ (1984) Longitudinal evaluation of hemodynamic changes in eclampsia. Am J Obstet Gynecol 150: 506

    PubMed  CAS  Google Scholar 

  35. Heilmann L, Beez M (1987) Neuere klinische Aspekte zur Hämodilution. Schattauer, Stuttgart

    Google Scholar 

  36. Heilmann L, Buchan PC (1984) Hemorheological disorders in obstetrics and neonatology. Schattauer, Stuttgart

    Google Scholar 

  37. Heilmann L, Kurz E (1977) Die Beschreibung einer einfachen Filtrationstechnik zur Erfassung der Erythrozyten–Verformbarkeit in der Schwangerschaft. Blut 35: 213–221

    Article  PubMed  CAS  Google Scholar 

  38. Heilmann L, Siekmann U, Schmid–Schönbein H (1985) Die Fließeigenschaften des Blutes in der Schwangerschaft. Dtsch Med Wochenschr 110: 1705–1709

    Article  CAS  Google Scholar 

  39. Heilmann L, Siekmann U, Schmid–Schönbein H, Ludwig H (1981) Hemoconcentration and pre–eclampsia. Arch Gynecol 231: 7–14

    Article  CAS  Google Scholar 

  40. Hobbs JB, Dats JN, Palmer AA, Long PA, Mitchell GM, Lou A, Mc Iver MA (1982) Whole blood viscosity in pre–eclampsia. Am J Obstet Gynecol 142: 288–292

    PubMed  CAS  Google Scholar 

  41. Hytten FE (1985) Blood volume changes in normal pregnancy. Clin Hematol 14: 601–610

    CAS  Google Scholar 

  42. Hytten FE, Paintin DB (1963) Increase in plasma volume during normal pregnancy. J Obstet Gynecol Br Commonw 70: 402–409

    Article  CAS  Google Scholar 

  43. Inglis TCM, Stuart J, George AJ, Davies AJ (1982) Haemostatic and rheological changes in normal pregnancy and pre–eclampsia. Br J Haematol 50: 461–465

    Article  PubMed  CAS  Google Scholar 

  44. Jaffe EA, Mosher DF (1978) Synthesis of fibronectin by cultured human endothelial cells. J Exp Med 147: 1779–1780

    Article  PubMed  CAS  Google Scholar 

  45. Jouppilu P, Kirkinen P, Punkker (1986) Correlation between umbilical vein blood flow and umbilical blood viscosity in normal and uncomplicated pregnancies. Arch Gynecol 237: 191–197

    Google Scholar 

  46. Kaibara M, Marumoto Y, Kobayashi T (1985) Erythrocyte filterability and fetal development in normal pregnancy. Am J Obstet Gynecol 152: 719–720

    PubMed  CAS  Google Scholar 

  47. Kagiya A, Shiratori H (1984) Systolic time intervals and impedance cardiogram in pregnant and toxemic women. Acta Obstet Gynecol Jpn 36: 1087–1094

    CAS  Google Scholar 

  48. Kiesewetter H (1983) Bedeutung hämorheologischer Meßverfahren für Diagnostik und Therapie von Durchblutungsstörungen. Essentialia 1: 151–161

    Google Scholar 

  49. Kirkpatrick FH, Hillmann DG, La Celle PL (1975) A 23187 and red cells: changes in deformability, K +, M2 +, Ca2+ and ATP. Experientia 31: 653–654

    Article  PubMed  CAS  Google Scholar 

  50. Koller O, Sagen N, Ulstein M, Vanla D (1979) Fetal growth retardation associated with inadäquad hemodilution in otherwise uncomplicated pregnancy. Acta Obstet Gynecol Scand 58: 9–14

    Article  PubMed  CAS  Google Scholar 

  51. Koller O (1982) The clinical significance of hemodilution during pregnancy. Obstet Gynecol Surv 37: 649–655

    Article  PubMed  CAS  Google Scholar 

  52. Lang SD, Lowe GDO, Walter JJ, Forbes CD, Prentice CRM, Calder AA (1984) Blood rheology in pre–eclampsia and intrauterine growth retardation: effect of blood pressure reduction with labetalol. Br J Obstet Gynaecol 91: 438–443

    Article  PubMed  CAS  Google Scholar 

  53. Larkin HE, Gallery DM, Hunyor SN, Györy AZ, Boyce ES (1980) Cardiac and hemodynamic measurements in hypertensive pregnancy. Clin Sei 59: 357–365

    Google Scholar 

  54. Liedtke B, Kiesewetter H, Jung F (1985) Comparative rheological invstigations in eclampsia. In: Goeke C (ed) Actual standing in EPH–gestosis. Elsevier Sei, Amsterdam

    Google Scholar 

  55. Liley AW (1970) Clinical and laboratory significance and variationes in maternal plasma volume in pregnancy. Int J Gynecol Obstet 8: 358–364

    Google Scholar 

  56. Mathews JD, Mason TW (1974) Plasma viscosity and pre–eclampsia. Lancet 1: 409

    Article  Google Scholar 

  57. Murphy JF, Riordan JO, Newcombe RG, Coles EC, Pearson JF (1986) Relation of hemoglobin level in first and second trimester to outcome of pregnancy. Lancet 11: 1992–1996

    Google Scholar 

  58. Ozanne P, Linderkamp O, Miller FC, Meiselmann HJ (1983) Erythrocyte aggregation during normal pregnancy. Am J Obstet Gynecol 147: 576–583

    PubMed  CAS  Google Scholar 

  59. Rafferty TD, Berkowitz PL (1980) Hemodynamics in patients with severe toxemia during labor and delivery. Am J Obstet Gynecol 138: 263–270

    PubMed  CAS  Google Scholar 

  60. Redman CW (1984) Maternal plasma volume and disorders of pregnancy. Br Med J 288: 295–296

    Article  Google Scholar 

  61. Sagen N, Nilsen ST, Kim HC, Kolöer O (1984) The predictive value of total extriol, HPL and Hb on perinatal outcome in severe pre–eclampsia. Acta Obstet Gynecol Scand 63:603–610

    Google Scholar 

  62. Sagen N, Haram K (1982) Hemoconcentration in severe pre–eclampsia. Br J Obstet Gynaecol 89: 802–804

    Article  PubMed  CAS  Google Scholar 

  63. Sagen N, Nilsen ST, Kim HC, Bergsjö P, Koller O (1984) Maternal hemoglobin concentration is closely related to birth weight in normal pregnancies. Acta Obstet Gynecol Scand 63: 245–249

    Article  PubMed  CAS  Google Scholar 

  64. Schönfeld K, Heilmann L, Bedow W, Fischer WM (in Vorbereitung) Hämorheologie des Nabelschnurblutes und fetale Flußmessung

    Google Scholar 

  65. Sibai BM, Anderson GD, Spinnato JA, Shaver DC (1983) Plasma volume findings in patients with mild pregnancy–induced hypertension. Am J Obstet Gynecol 147: 16–22

    PubMed  CAS  Google Scholar 

  66. Siekmann U (1985) Die Beziehungen zwischen der maternalen Hämodynamik und den Fließeigenschaften des Blutes in der Schwangerschaft. Habilitationsschrift, Essen

    Google Scholar 

  67. Stuart J (1985) Design principle for clinical and laboratory studies of erythrocyte deformability. Clin Hemorheol 5: 159–169

    Google Scholar 

  68. Stubbs THM, Jazarchick J, Hörger ED (1984) Plasma fibronektin levels in pre–eclampsia: a possible biochemical marker for vascular endothelial damage. Am J Obstet Gynecol 150: 885–890

    PubMed  CAS  Google Scholar 

  69. Strauss RG, Keefer JR, Burke T, Givetta JM (1980) Hemodynamic monitoring of cardiogenic edema complicating toxemia of pregnancy. Am J Obstet Gynecol 55: 170–175

    CAS  Google Scholar 

  70. Thornborn J, Drummond MM, Wigham KA, Lowe GDO, Forbes CD, Prentice CRM, Whitfield CR (1982) Blood viscosity and haemostatic factors in late pregnancy pre–eclampsia and fetal growth retardation. Br J Obstet Gynaecol 89: 117–122

    Article  Google Scholar 

  71. Worley RJ, Hentschel WM, Cormier C et al. (1982) Increased sodium–lithium countertransport in erythrocytes of pregnant women. N Engl J Med 307: 412–416

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Heilmann, L. (1989). Rheologie und Gestose. In: Hillemanns, H.G., Schillinger, H. (eds) Das Restrisiko gegenwärtiger Geburtshilfe. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74320-7_34

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-74320-7_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74321-4

  • Online ISBN: 978-3-642-74320-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics