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Traditions of Antihypertensive Therapy in Different Countries

  • Chapter
Pharmacology of Antihypertensive Therapeutics

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 93 / 1))

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Abstract

The therapy of hypertension has evolved over the past 50 years from the short-term care of a small number of hospitalized patients with severely elevated blood pressure and organ damage to a major community health problem involving a substantial proportion of the population with mild to moderate hypertension. In the beginning, severe side effects and toxicity of antihypertensive agents were accepted by patients and doctors as the price that had to be paid for this lifesaving therapy. The results of recent therapeutic trials show the benefits of antihypertensive treatment for mild to moderate hypertension. This has changed the attitudes towards treatment. The aim of modern antihypertensive therapy is the reduction of the risk of cardiovascular disease. The management of hypertensive patients therefore has to include the minimization of other controllable risk factors such as diabetes, hypercholesterolemia, alcohol, and cigarette smoking. Blood pressure lowering can be achieved not only by pharmacological substances but also by non-drug methods, e. g., reduction of sodium intake, reduction of body weight, reduction of alcohol intake, increased physical activity, and meditation. These methods are part of an antihypertensive strategy with different priorities in the European countries.

Professor Shkhvatsabaya died October 11th, 1988.

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Authors
  1. R. Lang
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  2. H. M. Steffen
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  3. W. Kaufmann
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  4. L. Wilhelmsen
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  5. J. I. S. Robertson
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  6. N. M. Kaplan
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  7. E. M. Krieger
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  8. L. O. T. Nascimento
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  9. O. L. Ramos
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  10. I. K. Shkhvatsabaya
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  11. L. S. Gong
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  12. W. Z. Zhang
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  13. H. Wang
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  14. Y. Kawano
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  15. T. Omae
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Editor information

Editors and Affiliations

  1. German Institute for High Blood Pressure Research and Department of Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, D-6900, Heidelberg, Germany

    Detlev Ganten M.D, Ph.D.

  2. Medical College of Ohio, CS10008, 300 Arlington Avenue, Toledo, OH, 43699, USA

    Patrick J. Mulrow M.D.

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Lang, R. et al. (1990). Traditions of Antihypertensive Therapy in Different Countries. In: Ganten, D., Mulrow, P.J. (eds) Pharmacology of Antihypertensive Therapeutics. Handbook of Experimental Pharmacology, vol 93 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74209-5_23

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  • DOI: https://doi.org/10.1007/978-3-642-74209-5_23

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