Abstract
Human leukocyte elastase (HLE) is a major protein of the azurophilic granules of human polymorphonuclear granulocytes (Fig.1). It is believed to be normally involved in the intracellular degradation of cellular and phagocytosed proteins and bacteria. Upon stimulation it is, however, released into extracellular space: into the plasma, where it is normally blocked by the α1-proteinase inhibitor (α1PI), and into mucous secretions, where it can be inhibited by the mucous proteinase inhibitor (MPI).
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© 1988 Springer-Verlag Berlin Heidelberg
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Bode, W. (1988). The Specific Interaction of Human Leukocyte Elastase with Various Protein Inhibitors. In: Winnacker, EL., Huber, R. (eds) Protein Structure and Protein Engineering. Colloquium der Gesellschaft für Biologische Chemie 14.–16. April 1988 in Mosbach/Baden, vol 39. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74173-9_9
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DOI: https://doi.org/10.1007/978-3-642-74173-9_9
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