Influence of Strontium Chloride on Blood Platelet Function

Abstract

Strontium appears to activate blood platelets by of its influx from a suspending medium (Blache et al 1987 a). Strong evidence that the same mechanism is activated by calcium throughout its channels, is however still lacking (Blache et al 1987 a; Blache et al 1987 b). This hypothesis derives from experiments carried out: a) on washed and resuspended platelets and not on intact platelets, as they are in platelet-rich plasma (PRP) and b) using thrombin as the only inducer of platelet reaction (Blache et al 1987a; Blache et al 1987b). Nevertheless, this data appears to be valid since, under the adopted experimental conditions, serotonin and thromboxane release was measured also in the presence or the absence of Ca²⁺ antagonists (Best et al 1981).