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[3H] Spiperone Binding to Lymphocytes in Psychiatric Disorders

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Neuropsychopharmacology

Abstract

There is ample evidence indicating that the central nervous system and the immune system are functionally linked. The exact mode of neural — immune interaction is still not certain, however the presence of specific neurotransmitter receptors on these cells appears to be important in mediating an intracellular event which could then lead to alterations in immune function. Several receptors for neurotransmitters in lymphocytes have been described, such as β-adrenergic receptors (Williams et al. 1976), muscarinic receptors (Strom et al. 1981), specific receptors for endorphines (Hazum et al. 1979), and even dopaminergic receptors (LeFur et al. 1980; Uzan et al. 1981; Ovadia and Abramsky 1987; Ebstein 1988).

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© 1990 Springer-Verlag Berlin Heidelberg

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Bondy, B., Peuker, B., Ackenheil, M. (1990). [3H] Spiperone Binding to Lymphocytes in Psychiatric Disorders. In: Bunney, W.E., Hippius, H., Laakmann, G., Schmauss, M. (eds) Neuropsychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74034-3_15

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  • DOI: https://doi.org/10.1007/978-3-642-74034-3_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74036-7

  • Online ISBN: 978-3-642-74034-3

  • eBook Packages: Springer Book Archive

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