Skip to main content

Naturally Occurring Anti-MHC Class I Antibodies in the Rat

  • Conference paper
MHC + X
  • 54 Accesses

Abstract

Immunity to major histocompatibility complex (MHC) determined antigens is usually studied after deliberate immunization or pregnancy, but can also be detected serologically in the absence of prior intentional immunization, notably against class I antigens. Our studies in the rat, a preliminary report of which has been published previously (Günther et al. 1983), were initiated by the observation that rat sera to be used as normal sera in hemagglutination assays occasionally agglutinated the red blood cells (RBCs).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Butcher GW, Howard JC (1986) The MHC of the laboratory rat, Rattus norvegicus. In: Weir DM (ed) Handbook of experimental immunology, vol 3. Blackwell, Oxford, pp 101.1–101.18

    Google Scholar 

  • Günther E, Elsässer-Beile U, Hedrich HJ (1983) Occurrence of antibodies against RT1.A antigens in normal rat sera. Transplant Proc 15: 1560–1561

    Google Scholar 

  • Klöting I, Stark O (1985) Occurrence of antibodies against gene products of the major histocompatibility complex in normal sera of diabetes-prone BB rats. Folia Biol (Praha) 31: 34–37

    Google Scholar 

  • Stock W, Günther E (1982) Serologic and cellular characterization of products of a new major histocompatibility gene region, RT1.C, of the rat; possible homology to mouse H-2Qa. J Immunol 128: 1923–1928

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Günther, E. (1988). Naturally Occurring Anti-MHC Class I Antibodies in the Rat. In: Ivanyi, P. (eds) MHC + X. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74026-8_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-74026-8_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74028-2

  • Online ISBN: 978-3-642-74026-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics