Abstract
Proximal tubular epithelial cells have the capacity of regulatory volume decrease (RVD) (Dellasega and Grantham 1973; Lohr and Grantham 1986; Kirk et al. 1987a, 1987b). The RVD response in proximal tubular epithelial cells is due to the loss of cytosolic potassium and chloride (e.g. Kirk et al. 1987a, 1987b). An important function of the RVD response in cells performing transcellular transport (e.g., proximal tubule) is to minimize cell swelling associated with acute imbalances in the rates of cell solute entry and exit (Schultz and Hudson 1986).
The work was supported by the Sonderforschungsbereich 156 of the Deutsche Forschungsgemeinschaft and by the Schweizer Nationalfonds (grant Nr. 3.882.085).
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© 1989 Springer-Verlag Berlin Heidelberg
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Ubl, J., Murer, H., Kolb, HA. (1989). Osmotically Activated Ion Channels in Membranes of Opossum Kidney Cells. In: Rettig, R., Ganten, D., Luft, F.C. (eds) Salt and Hypertension. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73917-0_3
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DOI: https://doi.org/10.1007/978-3-642-73917-0_3
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