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Models, Mechanisms and Kinetics of Neuromuscular Synapse Elimination in Reinnervated Adult Skeletal Muscle

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Post-Lesion Neural Plasticity

Introductory Overview

The elimination of polyneuronal innervation of muscle fibres in immature skeletal muscle is well documented (see review by Bennett 1983). The main purpose of this chapter is to address briefly the issue of polyneuronal innervation and its elimination in reinnervated adult muscle, especially following injury to part of its nerve supply. The repair of connections in partially denervated muscle sometimes occurs with only limited success. This topic is therefore germane to the failure of reorganization of neuronal convergence and divergence in the injured central nervous system, because it is more comparable than, say, reinnervation of completely denervated muscle, which is usually completely successful.

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Authors and Affiliations

  1. Department of Physiology, University Medical School, Teviot Place, Edinburgh, EH8 9AG, Great Britain

    R. R. Ribchester

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  1. R. R. Ribchester
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Editors and Affiliations

  1. Dept. of Neurobiology, University of Bremen, NW2, Postfach 330440, D-2800, Bremen 33, Federal Republic of Germany

    Hans Flohr

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© 1988 Springer-Verlag Berlin Heidelberg

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Ribchester, R.R. (1988). Models, Mechanisms and Kinetics of Neuromuscular Synapse Elimination in Reinnervated Adult Skeletal Muscle. In: Flohr, H. (eds) Post-Lesion Neural Plasticity. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73849-4_2

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  • DOI: https://doi.org/10.1007/978-3-642-73849-4_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73851-7

  • Online ISBN: 978-3-642-73849-4

  • eBook Packages: Springer Book Archive

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