Abstract
Inflammation is a series of events which in part follow each other and in part are contemporary. The acute phase is followed by resolution or the healing phase. A variety of enzymes and their natural inhibitors are known to operate in the inflammatory process.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Allison AC (1969) Lysosomes. In:Bittar EE, Bittar N (eds) The biologic basis of medicine, vol 1. Academic, New York, pp 209–242
Allison AC, Paton GR (1965) Chromosome damage in human diploid cells following activation of lysosomal enzymes. Nature 207:1170–1173
Allison AC et al. (1966) The role of lysosomes and of cell membranes in photosensitization. Nature 209:874–878
Allison AC et al. (1968) An examination of the growth of cells in tissue culture. Proc Soc Exp Biol Med 126:112–114
Astrup T (1968) Blood coagulation and fibrinolysis in tissue culture and tissue repair. Biochem Pharmacol [Suppl] 17:241–257
Baggiolini M et al. (1978) Subcellular localization of granulocyte enzymes. In:Havemann K, Janoff A (eds) Neutral proteases of human polymorphonuclear leukocytes. Urban and Schwarzenberg, Baltimore, pp 3–17
Barrett AJ (1977) Cathepsin D and other carboxyl proteinases. In:Barrett AJ (ed) Proteinases in mammalian cells and tissues. North-Holland, Amsterdam, pp 209–248
Bentley C et al. (1976) In vitro synthesis of factor B of the alternative pathway of complement activation by mouse peritoneal macrophages. Eur J Immunol 6:393–398
Bleumink E, Doeglas HMG (1977) Deflciences of protease inhibitors in patients with skin diseases. Dermatologica 154:305
Bleumink E, Doeglas HMG (1980) Protease inhibitor deflciences in a patient with angioedema:results of family studies. Br J Dermatol 102:473
Bosman HB (1969) Glycoprotein degradation. Glycosidases in fibroblasts transformed by oncogenic viruses. Exp Cell Res 54:217–221
Bosman HB (1972) Elevated glycosidases and proteolytic enzymes in cells transformed by RNA tumor virus. Biochim Biophys Acta 264:339–343
Bosman HB et al. (1974) Surface biochemical changes accompanying primary infection with Rous sarcoma virus. II. Proteolytic and glycosidase activity and sublethal autolysis. Exp Cell Res 83:25–30
Braun-Falco O et al. (1977) Immunoelectronmicroscopical demonstration of in vivo bound complement C3 in psoriatic lesions. Arch Dermatol Res 260:57–62
Burckhardt W (1941) Untersuchungen über die Photoaktivitat einiger Sulfanilamide. Dermatologica 83:63–68
Burger M (1970) Proteolytic enzymes initiating cell division and escape from contact inhibition of growth. Nature 227:170–171
Christman JK et al. (1977) Plasminogen activators. In:Barrett AJ (ed) Proteases in mammalian cells and tissues. North Holland, Amsterdam, pp 91–149
Cochrane CG et al. (1959) The role of polymorphonuclear leukocytes in the initiation and cessation of the Arthus vasculitis. J Exp Med 110:481
Cormane RH et al. (1979) Immunologic implications of PUVA therapy in psoriasis vulgaris. Arch Dermatol Res 265:245–267
Davies P, Allison AC (1976) Secretion of macrophage enzymes in relation to the pathogenesis of chronic inflammation. In:Nelson DS (ed) Immunobiology of the macrophages. Academic, New York, p 427
Desai ID et al. (1964) Peroxidative and radiation damage to isolated lysosomes. Biochem Biophys Acta 86:277–285
Dingle JT et al. (1973) Immunoinhibition of intracellular protein digestion in macrophages. J Exp Med 137:1124–1141
Doeglas HMG, Bleumink E (1974) Familial cold urticaria:clinical findings. Arch Dermatol 110:382–388
Donaldson VH, Evans RR (1973) Biochemical abnormality in hereditary angioneurotic oedema:absence of serum inhibitor of C1 esterase. Am J Med 35:37–44
Eftekhari N et al. (1980) Protease inhibitor profiles in urticaria and angioedema. Br J Dermatol 103:33–39
Fehr K et al. (1974) Digestion of autologous IgG by acid lysosomal protease (cathepsin D) and its role in immune complex formation and inflammation. Adv Clin Pharmacol 6:64
Fine RM et al. (1979) Accumulation of cancer-related glycoprotein, EDCI, in psoriasis. J Invest Dermatol 73:264–265
Fräki JE (1976) Human skin proteases. Separation and characterization of two acid proteases resembling cathepsin B1 and cathepsin D and of an inhibitor to cathepsin B1. Arch Dermatol Res 255:317
Fräki JE, Hopsu-Havu VK (1972) Human skin proteases. Differential extraction of proteases and of endogenous protease inhibitors. Arch Dermatol Forsch 242:329–342
Fräki JE, Hopsu-Havu VK (1975) Human skin proteases. Separation and characterization of two alkaline proteases, one splitting trypsin and the other chymotrypsin substrates. Arch Dermatol Res 253:261–276
Fräki JE, Hopsu-Havu VK (1976) Human skin proteases. Fractionation of psoriasis scale proteases and separation of a plasminogen activator and a histone hydrolysing protease. Arch Dermatol Res 256:113–126
Fräki JE, Hopsu-Havu VK (1977) Inhibition of human skin proteinases by chloroquine, dapsone and sulfapyridine. Arch Dermatol Res 259:113–115
Fräki JE et al. (1978) Plasminogen activators of psoriatic scale extracts. Separation of two plasminogen activators by isoelectric focusing. Arch Dermatol Res 261:259–266
Fräki JE et al. (1979) Proteinase binding and enhancing factor in human skin. Arch Dermatol Res 264:185–191
Fritz H (1980) Proteinase inhibitors in severe inflammatory processes (septic shock and experimental endotoxaemia):biochemical, pathophysiological and therapeutic aspects. Ciba Found Symp 75:351–379
Fruton JS (1946) On the proteolytic enzymes of animal tissues. V. Peptidases of skin, lung and serum. J Biol Chem 166:721–738
Gadek JE et al. (1980) Replacement of therapy in hereditary angioedema:successful treatment of acute episodes of angioedema with partly purified C1 inhibitor. N Engl J Med 302:542–546
Ginsburg I et al. (1977) The role played by leukocyte extracts and inflammatory exudates in the release of lipopolysaccharides from Gram-negative bacteria:relation to tissue damage induced during infection. In:Willoughby DA, Giroud JP, Velo GP (eds) Per-spectives in inflammation. MTX Lancaster, England, pp 163–167
Glenner GG, Cohen LA (1960) Histochemical demonstration of a species specific trypsin-like enzyme in mast cells. Nature 185:846–847
Glenner GG et al. (1962) Histochemical demonstration of a trypsin-like esterase activity in mast cells. J Histochem Cytochem 10:109–110
Goldstein IM (1975) Effect of steroids on lysosomes. Transplant Proc 7:21–24
Goldstein IM, Weissmann G (1974) Generation of C5-derived lysosomal enzyme releasing activity (C5a) by lysates of leukocyte lysosomes. J Immunol 113:1583–1588
Gordon S (1976) Macrophage neutral proteinases and chronic inflammation. Ann NY Acad Sci 278:176–189
Greenbaum LM (1979) Kininogenases in blood cells. In:Erdös ED (ed) Bradykinin, kallidin and kallikrein. Springer, Berlin Heidelberg New York, pp 91–102 (Handbook of experimental pharmacology, vol 25, supplement)
Hällgren R, Venge P (1976) Cationic proteins of human granulocytes:enhancement of phagocytosis by staphylococcus protein A-IgG complexes. Inflammation 1:237–246
Hammarström S et al. (1975) Increased concentrations of non-esterifled arachidonic acid 12:-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2 and prostaglandin F2 in epidermis of psoriasis. Proc Natl Acad Sci USA 72:5130–5134
Hayashi H (1975) The intracellular neutral SH-dependent protease associated with inflammatory reactions. Int Rev Cytol 40:101–151
Hayashi H et al. (1975) The nature of a mediator of leukocyte chemotaxis in inflammation. Antibiot Chemother 19:296–332
Hibino T et al. (1980) In vitro and in vivo inhibition of rat liver cathepsin L by epidermal proteinase inhibitor. Biochem Biophys Res Commun 93:440–447
Hönigsmann H et al. (1974) Epidermal lysosomes and ultraviolet light. J Invest Dermatol 63:337–342
Hopsu-Havu VK, Ekfors TO (1969) Identification in the rat skin and subcutaneous granuloma of an enzyme liberating N-terminal glycyl-proline from peptides. Arch Klin Exp Dermatol 235:301–307
Hopsu-Havu VK, Fräki JE (1980) Proteinases and their inhibitors in skin diseases. Int J Dermatol 20:159–163
Hopsu-Havu VK, Glenner GG (1966) A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-beta-naphthylamide. Histochemie 7:197–201
Hopsu-Havu VK, Jansén CT (1968) Biochemical demonstration of an aminopeptidase in rat skin specific for N-terminal basic amino acids (aminopeptidase B). Arch Klin Exp Dermatol 233:1–10
Hopsu-Havu VK et al. (1970) Partial purification and characterization of an acid dipeptide naphthylamidase (carboxytripeptidase) of the rat skin. Arch Klin Exp Dermatol 236:282–296
Hopsu-Havu VK et al. (1977) Proteolytic enzymes in the skin. In:Barrett AJ (ed) Proteinases in mammalian cells and tissues. Elsevier, North-Holland, Amsterdam New York Oxford, pp 545–581
Houck JC, Patel YM (1965) Proposed mode of action of corticosteroids on the connective tissue. Nature 206:158–160
Houck JC et al. (1967) The effects of anti-inflammatory drugs upon the chemistry and enzymology of rat skin. Biochem Pharmacol 16:1099–1111
Houck JC et al. (1968) Induction of collagenolytic and proteolytic activities by anti-inflammatory drugs in the skin and fibroblast. Biochem Pharmacol 17:2081–2090
Hugon J, Borgers M (1965) The ultrastructural localization of acid phosphatase in the crypt epithelium of the irradiated mouse duodenum. J Histochem Cytochem 13:526–525
Izaki S et al. (1979) Fibrin deposition and clearance in chronic granulomatous inflammation:correlation with T-cell function and proteinase inhibitor activity in tissue. J Invest Dermatol 73:561–565
Jablonska S et al. (1979) Ist die Psoriasis eine autoimmune Erkrankung? Hautarzt 30:634–539
Järvinen M (1976) Purification and properties of two protease inhibitors from rat skin inhibiting papain and other SH-protease. Acta Chem Scand [B] 30:933–940
Järvinen M, Hopsu-Havu VK (1975) α-N-benzoylarginine-2-naphthyl-amide hydrolase (cathepsin B1?) from rat skin. II. Purification of the enzyme and demonstration of two inhibitors in the skin. Acta Chem Scand [B] 29:772–780
Järvinen M et al. (1978) The low-molecular-weight SH-protease inhibitor in rat skin is epidermal. J Invest Dermatol 71:119–121
Janoff A (1970) Mediators of tissue damage in leukocyte lysosomes. X. Further studies on human granulocyte elastase. Lab Invest 22:228
Janoff A (1972) Neutrophil proteases in inflammation. Annu Rev Med 23:177–190
Janoff A, Zeligs JD (1968) Vascular injury and lysis of basement membrane in vitro by neutral proteinase of human leukocytes. Science 162:702–704
Junnila SK et al. (1971) Elastase and trypsin inhibitors of human skin and serum. Partial purification and characterization. Acta Derm Venereol (Stockh) 51:251–256
Kass EH, Wolff SM (1973) Bacterial lipopolysaccharides, chemistry, biology and clinical significance of endotoxins. University of Chicago Press, Chicago
Kocmierska-Grodzka D, Goutier R (1971) Investigation on the catheptic activity of liver in irradiated rats. Strahlentherapie 142:345–348
Koob TJ et al. (1974) Regulation of human skin collagenase activity by hydrocortisone and dexamethasone in organ culture. Biochem Biophys Res Commun 61:1083–1088
Koono M et al. (1968) Proteases associated with Arthus skin lesions:their purification and biological significance. Tohoku J Exp Med 94:231
Krogh HK (1970) The occurrence of antibodies to stratum corneum in man. Int Arch Allergy Appl Immunol 37:649–659
Kueppers F, Bearn AG (1966) A possible experimental approach to the association of hereditary alpha-1-antitrypsin deficiency and pulmonary emphysema. Proc Soc Exp Biol Med 121:1207–1209
Lazarus GS (1974) The role of neutral proteinase and cathepsin D in turpentine induced inflammation. J Invest Dermatol 62:367–371
Lazarus GS et al. (1968) Degradation of collagen by a human granulocyte collagenolytic system. J Clin Invest 47:2622–2629
Lazarus GS et al. (1975) Lysosomes and the skin. J Invest Dermatol 65:259–271
Lazarus GS et al. (1977) Polymorphonuclear leukocytes:possible mechanism of accumulation in psoriasis. Science 198:1162–1163
Lie SO, Schofleld B (1973) Inactivation of lysosomal functions in normal cultured human fibroblasts by chloroquine. Biochem Pharmacol 22:3109–3114
Lin T-Y, Williams HR (1975) Inhibition of the local haemorrhagic Shwartzman reaction by an acid proteinase. Experientia 31 (2):209–212
Lycke AWJ et al. (1967) Effects of Cortisol released cutaneous protease upon the permeability of the micro-circulation. J Invest Dermatol 48:318–325
Mathews KP et al. (1980) Familial carboxypeptidase N deficiency. Ann Intern Med 93:443–445
McClelland DBL, Van Furth R (1976) In vitro synthesis of B1C/B1 globulin (the C3 component of complement) by tissues and leukocytes of mice. Immunology 31:855
Mier PD, Van den Hurk JJMA (1975) Inhibition of lysosomal enzymes by dapsone. Br J Dermatol 93:471–472
Mier PD, Van den Hurk JJMA (1976 a) Acid hydrolases in psoriatic epidermis. Br J Dermatol 94:219–220
Mier PD, Van den Hurk JJMA ( 1976 b) Lysosomal hydrolases of the epidermis. 4. Overall profile in comparison with dermis and other tissues. Br J Dermatol 94:443–446
Minta JO, Movat HZ (1979) The complement system and inflammation. In:Movat HZ (ed) Inflammatory reaction. Curr Top Pathol 68:135–178
Miyamoto M, Terayama H (1973) Serum factors affecting cathepsin release from lysosomes. Biochem Biophys Res Commun 64:617–624
Movat HZ (1979 a) The kinin system and its relations to other systems. Curr Top Pathol 68:111–134
Movat HZ (1979 b) The plasma kallikrein-kinin system and its interrelationship with other components of blood. In:Erdös EG (ed) Bradykinin, kallidin and kallikrein. Springer, Berlin Heidelberg New York, pp 1–89 (Handbook of experimental pharmacology, vol 25, Supplement)
Murphy G et al. (1977) Collagenase is a component of the specific granules of human neutrophil leukocytes. Biochem J 162:195–197
Neufahrt A, Henckel S (1974) Fraktionierte Zentrifugation und Gelfiltration zur Trennung von Proteinasen aus Psoriasisschuppen. Arch Dermatol Forsch 250:127–136
Odeberg H et al. (1975) Cationic proteins of human granulocytes. IV. Esterase activity. Lab Invest 32(1):86–90
Ohlsson K, Ohlsson I (1973) The neutral proteases of human granulocyte. Isolation and partial characterization of two granulocyte collagenases. Eur J Biochem 36:473–481
Ohyama T (1974) A neutral inflammatory protease associated with Arthus skin lesion in guinea pig. Tohoku J Exp Med 113:231
Olson RL, Nordquist RE (1966) Ultramicroscopic localization of acid phosphatase in human epidermis. J Invest Dermatol 46:431
Ossowski L et al. (1973) An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses. J Exp Med 137:112–126
Page RC et al. (1974) Participation of mononuclear phagocytes in chronic inflammatory diseases. J Reticuloendothel Soc 15:413–438
Paris JE et al. (1969) Distribution and properties of lysosomal enzymes in untreated and in irradiated mouse mammary-gland carcinomas. JNCI 42:383–398
Peavy DL et al. (1972) Selective effect of bacterial endotoxins on various subpopulations of lymphoreticular cells. J Infect Dis 128 (Suppl):83
Postlethwaite AE et al. (1976) The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor. J Exp Med 144:1188–1203
René AA, Evans AS (1970) Correlation of radiation-induced ultrastructural changes in mouse hepatocytes with alterations in plasma concentration of protein-bound neutral hexoses. Radiat Res 44:224–236
René AA et al. (1971) Radiation-induced ultrastructural and biochemical changes in lysosomes. Lab Invest 25:230–239
Ruddy S et al. (1972) The complement system of man. I. N Engl J Med 287:489–495
Ryan GB, Majno G (1977) Acute inflammation. Am J Pathol 86:185–276
Ryan TJ et al. (1971) Epithelial-endothelial interaction in the control of inflammation through fibrinolysis. Br J Dermatol 84:501–515
Ryan WL, Cardin C (1967) Lysosomal stimulation and inhibition of the growth of cells in tissue cultures. Proc Soc Exp Biol Med 126:112–114
Sasaki M et al. (1977) A new serum component which specifically inhibits thiol proteinases. Biochem Biophys Res Commun 76:917–924
Schmidt W, Havemann K (1974) Isolation of elastase-like and chymotrypsin-like neutral proteases from human granulocytes. Hoppe-Seylers Z Physiol Chem 355:1077–1082
Schnebli HP, Burger M (1972) Selective inhibition of growth of transformed cells by protease inhibitors. Proc Natl Acad Sci USA 69:3825–3827
Schorlemmer HU, Allison AC (1976) Effects of activated complement components on enzyme secretion by macrophages. Immunology 31:781
Schorlemmer HU et al. (1976) Ability of activated complement components to induce lysosomal enzyme release from macrophages. Nature 261:48
Schorlemmer HU et al. (1977) Interactions of macrophages and complement components in the pathogenesis of chronic inflammation. In:Willoughby DA, Giroud JP, Velo GP (eds) Perspectives in inflammation. MTX, Lancaster, England, pp 191–206
Schulz KH (1974) Hereditäres Quicke-Ödem. Neuere Wege der Therapie. Hautarzt 25:12–16
Schwartze G, Hanson H (1971) Zur proteolytischen Aktivität in Psoriasisschuppen. Dermatol Monatsschr 157:315–325
Seltzer JL et al. (1978) A component of normal human serum which enhances the activity of vertebrate collagenases. Biochem Biophys Res Commun 80:637–645
Seppä HJ (1978) Rat skin main neutral protease:immunohistochemical localization. J Invest Dermatol 71:311–315
Smolen JE, Weissmann G (1978) The granulocyte:metabolic properties and mechanisms of lysosomal enzyme release. In:Havemann K, Janoff A (eds) Neutral proteases of human polymorphonuclear leukocytes. Urban and Schwarzenberg, Munich, pp 56–76
Starkey PM (1977) Elastase and cathepsin G:the serine proteinases of human neutraphil leucocytes and spleen. In:Barrett AJ (ed) Proteinases in mammalian cells and tissues. North-Holland, Amsterdam, pp 57–89
Starkey PM, Barrett AJ (1973) Human cathepsin Bt. Inhibition by α2-macroglobulin and other serum proteins. Biochem J 131:823–831
Starkey PM, Barrett AJ (1976 a) Human lysosomal elastase. Catalytic and immunological properties. Biochem J 155:265–271
Starkey PM, Barrett AJ (1976 b) Human cathepsin G. Catalytic and immunological properties. Biochem J 155:273–278
Steigleder GK, Blomayer U (1964) Zur Biochemie der krankhaften Verhoraung, im besonderen bei Psoriasis. Arch Klin Exp Dermatol 218:461–468
Stetson CA Jr (1951) Similarities in the mechanisms determining the Arthus and Shwartzman phenomenon. J Exp Med 94:347
Stricklin GP et al. (1977) Human skin collagenase:isolation of precursor and active forms from both fibroblast and organ cultures. Biochemistry 16:1607–1615
Stüttgen G, Schilling T (1959) On the influenceability of proteolysis of human skin by prednisolone, kallikrein inactivator and roentgen rays. Z Gesamte Exp Med 132:51–63
Stüttgen G, Würdemann I (1959) Zur Darstellung der kateptischen Endopeptidase in der normalen menschlichen Haut und bei Dermatosen. Arch Klin Exp Dermatol 208:192–203
Tagami H, Ofuji S (1977) Characterization of a leukotactic factor derived from psoriatic scale. Br J Dermatol 97:509–518
Thomas CA et al. (1977) Cellular serine proteinase induced chemotaxis by complement activation. Nature 269:521–522
Thomson AW et al. (1978) Effects of the antiprotease Transylol on peripheral blood leukocytes. Experientia 34:528–530
Thorne KJ et al. (1976) Lysis and killing of bacteria by lysosomal proteinases. Infect Immun 14:555–563
Tokaji G (1971) The chemical pathology of thermal injury, with special reference to burns SH-dependent protease and its inhibitor. Kumamoto Med J 24:68–86
Toki N, Yamura T (1978) Plasma-kinin-forming enzyme in human skin. I. Extraction and column chromatographic of plasma-kinin-forming enzyme and its inhibitor. Acta Derm Venereol (Stockh) 58 (5):395–399
Unkeless JC et al. (1973) An enzymatic function associated with transformation of fibroblasts by oncogenic virus. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses. J Exp Med 137:85–111
Unkeless JC et al. (1974) Fibrinolysis associated with oncogenic transformation. Partial purification and characterization of the factor, a plasminogen activator. J Biol Chem 249:4295–4305
Vassalli JD et al. (1976) Macrophage plasminogen activator:modulation of enzyme production by anti-inflammatory steroids, mitotic inhibitors and cyclic nucleotides. Cell 8:271–281
Venge P, Olsson I (1975) Cationic proteins of human granulocytes. VI. Effects on the complement system and mediation of chemotactic activity. J Immunol 115:1505–1508
Vischer TL et al. (1976) In vitro stimulation of lymphocytes by neutral proteinases from human polymorphonuclear leukocyte granules. J Exp Med 144:863–872
Volden G (1978) Acid hydrolases in blister fluid. 4. Influence of ultraviolet radiation. Br J Dermatol 99:53–60
Volden G, Thune PO ( 1979 a) Acid hydrolases in blister fluid. 5. Influence of ultraviolet radiation in patients with polymorphic light eruption. Br J Dermatol 100:277–282
Volden G, Thune PO ( 1979 b) Acid hydrolases in blister fluid. 6. Photocontact and contact allergic skin reactions. Br J Dermatol 100:283–289
Volden G et al. (1980) Release of intracellular enzymes from cutaneous cells after non-necrotizing damage by ultraviolet light. Arch Dermatol Res 268:225–230
Wahl LM et al. (1974) Collagenase production by endotoxin-activated macrophages. Proc Natl Acad Sci USA 71:3598–3601
Wakulchik SD et al. (1980) Photolysis of protoporphyrin-treated human fibroblasts in vitro:studies on the mechanism. J Lab Clin Med 96:158–167
Ward PA, Cochrane CG (1965) Bound complement and immunologic injury of blood vessels. J Exp Med 121:215–234
Ward PA, Hill JH (1970) C5 chemotactic fragments produced by an enzyme in lysosomal granules of neutrophils. J Immunol 104:535–543
Ward PA et al. (1972) Leukotactic factors elaborated by virus-infected tissue. J Exp Med 135:1095–1103
Ward PA et al. (1978) The modulation by neutral proteases and other factors from neutrophils. In:Havemann K, Janoff A (eds) Neutral proteases of human polymorphonuclear leukocytes. Urban and Schwarzenberg, Munich, pp 276–286
Weissmann G, Dingle J (1961) Release of lysosomal protease by ultraviolet irradiation and inhibition by hydrocortisone. Exp Cell Res 25:207–210
Weissmann G, Fell HB (1962) The effect of hydrocortisone of the response of fetal rat skin in culture to ultraviolet irradiation. J Exp Med 116:365–380
Werb Z, Gordon S (1975 a) Secretion of a specific collagenase by stimulated macrophages. Z Exp Med 142:346–360
Werb Z, Gordon S (1975 b) Elastase secretion by stimulated macrophages. Characterization and regulation. J Exp Med 142:361–377
Wibo M, Poole B (1974) Protein degradation in cultured cells. II. The uptake of chloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B1 J Cell Biol 63:430–440
Wilkinson PC (1974) Chemotaxis and inflammation. Churchill Livingstone, London Willis I, Kligman AM (1968) The mechanism of photoallergie contact dermatitis. J Invest Dermatol 51:378
Willoughby DA (1978) Inflammation. Endeavour 2:57–65
Yu RJ et al. (1972) Inhibition of keratinases by α2-macroglobulin. Experientia 28:886
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Volden, G., Hopsu-Havu, V.K. (1989). Proteolytic Enzymes in Relation to Skin Inflammation. In: Greaves, M.W., Shuster, S. (eds) Pharmacology of the Skin I. Handbook of Experimental Pharmacology, vol 87 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73797-8_27
Download citation
DOI: https://doi.org/10.1007/978-3-642-73797-8_27
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-73799-2
Online ISBN: 978-3-642-73797-8
eBook Packages: Springer Book Archive