Abstract
Apart from its integumentary function, one of the principal functions of the skin is in thermoregulation. Central temperature depends upon the balance between heat production and heat loss, and, apart from a normally small contribution from the respiratory system, heat loss is entirely mediated by the skin. Two mechanisms contribute to this action: control of skin blood flow and thermal sweating. These mechanisms are to some extent interdependent: alteration of blood flow alone can influence heat loss, but sweating, and increased evaporative heat loss from skin, requires vasodilatation to provide water for evaporation and increased heat flow (and hence blood flow) to the skin surface.
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Cranston, W.I. (1989). Thermoregulation and the Skin. In: Greaves, M.W., Shuster, S. (eds) Pharmacology of the Skin I. Handbook of Experimental Pharmacology, vol 87 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73797-8_12
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DOI: https://doi.org/10.1007/978-3-642-73797-8_12
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