Prevention of Traveler’s Diarrhea: A Double-Blind Randomized Trial with Saccharomyces cerevisiae Hansen CBS 5926



“Travel broadens the mind and loosens the bowels.” This metaphor of Sherwood L. Gorbach outlines the problem of traveler’s diarrhea in modern tourism. With an attack rate of 25%–50% diarrheal illness may affect more than four million visitors from industrialized countries annually, of whom 30% are ill enough to be confined to bed and 40% have to alter their scheduled activities [1].


Attack Rate Prophylactic Efficacy Diarrheal Illness Significant Statisti Consensus Development Conference Statement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Gorbach SL (1987) Bacterial diarrhea and its treatment. Lancet II:1378–1382CrossRefGoogle Scholar
  2. 2.
    DuPont HL, Ericsson CD, Johnson PCJ (1985) Chemotherapy and chemoprophy-laxis of traveller’s diarrhea. Ann Intern Med 102(2):260–261PubMedGoogle Scholar
  3. 3.
    Consensus Development Conference Statement (1986) Rev Inf Dis [Suppl 2]8: S227-S233Google Scholar
  4. 4.
    Steffen R, Heusser R, DuPont HL (1986) Prevention of traveller’s diarrhea by nonantibiotic drugs. Rev Infect Dis [Suppl 2]8:S151-S159PubMedCrossRefGoogle Scholar
  5. 5.
    Adkins HJ, Escamilla J, Santiago LT, Ranoa C, Echeverria P, Cross JH (1987) Two-year survey of etiologic agents of diarrheal diseases at San Lazaro Hospital, Manila, Rep. of Philippines. J Clin Microbiol 25(7):1143–1147PubMedGoogle Scholar
  6. 6.
    Taylor DN, Echeverria P, Blaser MI, Pitarangsi C, Blacklow N, Cross I (1985) Polymicrobial aetiology of traveller’s diarrhea. Lancet I:381–383CrossRefGoogle Scholar
  7. 7.
    DuPont HL, Sullivan P, Evans EG, Pickering LK, Evans DJ, Vollet J, Ericsson CD et al. (1980) Prevention of traveller’s diarrhea (emporiatric enteritis): prophylactic administration of subsalicylate bismuth. JAMA 243:237–241PubMedCrossRefGoogle Scholar
  8. 8.
    Cotte J (1967) Expertise biologique concernant l’activité saccarisique de Saccharo-myces boulardii 17 lyophilisée. VerdictGoogle Scholar
  9. 9.
    Brugier S, Patte F (1975) Antagonisme in vitro entre l’ultralevure et different germs bacteriens. Med Paris 45:3–8Google Scholar
  10. 10.
    Riggi SI, di Luzio NR (1961) Identification of a reticuloendothelial stimulating agent in zymosan. Am J Physiol 200:297–300PubMedGoogle Scholar
  11. 11.
    Petzold K, Müller E (1986) Animal experimental and cell biological studies on the effect of Saccharomyces cerevisiae Hansen CBS 5926 on the unspecific enhancement of the resistance to infection. Drug Res 36[2]:1085–1088Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

There are no affiliations available

Personalised recommendations