Abstract
In a situation of growing environmental pollution, human population is exposed to a large number of chemical substances, which are extremely complex in nature. In the ambient air many known mutagens and carcinogens have been detected, which can lead to health hazards by respiration (1,2). According to epidemiological studies, there is evidence that air pollution may be a contributory factor to the increased risk for lung cancer among human population (3, 4). For this reason, early and rapid detection of the mutagenic and carcinogenic potential of harmful substances occurring in the atmosphere is of great importance (5). Since most mutagens and carcinogens produce cytologically visible damage to chromosomes(6), cytogenetic short term tests using human and rodent tissue culture cells seems to be of considerable value for predicting a genotoxic potential of environmental pollutants. On this base we have carried out a comparative study with a particulate extract of city smog and of automobile exhaust, respectively
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© 1988 Springer-Verlag Berlin Heidelberg
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Hadnagy, W., Seemayer, N.H. (1988). Evaluation of Genotoxic Effects by Environmental Pollutants Using Cell Culture Systems. In: Seemayer, N.H., Hadnagy, W. (eds) Environmental Hygiene. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73766-4_7
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DOI: https://doi.org/10.1007/978-3-642-73766-4_7
Publisher Name: Springer, Berlin, Heidelberg
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