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Die Bedeutung von Calmodulin und Kalzium für die Wundheilung

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Gegenwärtiger Stand der operativen Dermatologie

Part of the book series: Fortschritte der operativen Dermatologie ((OP.DERMATOLOGIE,volume 4))

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Zusammenfassung

Calmodulin (CaM) ist ein multifunktionales kalziumabhängiges Modulatorprotein, das in nahezu allen Eukaryozyten gefunden wird (Cheung 1980). Als zentraler Mediator des zellulären Kalzium-Signals steuert es z.B. den Ca2+-Transport, die Neurotransmitterausschüttung, Steroidsynthese, Mitosen und Zellbewegungen. Es reguliert Enzymaktivitäten, wie z. B. die Adenylatzyklase, cAMP-Phosphodiesterase (PDE) und Ca2+-Mg2+-ATPase, Phosphorylase-Kinase, Phospholipase A2 und NAD-Kinase (Marmé 1981).

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Literatur

  • Butcher RW, Sutherland EW (1962) Adenosine-3′, 5′-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine-3′, 5′ phosphate in human urine. J Biol Chem 237:1244–1250

    CAS  PubMed  Google Scholar 

  • Cheung WY (1970) Cyclic 3′, 5′-nucleotide phosphodiestease, demonstration of an activator. Biochem Biophys Res Comm 38:533–538

    Article  CAS  PubMed  Google Scholar 

  • Cheung WY (1971) Cyclic 3′, 5′-nucleotide phosphodiesterase, evidence for and properties of a protein activator. J Biol Chem 246:2859–2869

    CAS  PubMed  Google Scholar 

  • Cheung WY (1980) Calmodulin plays a pivotal role in cellular regulation. Science 207:19–27

    Article  CAS  PubMed  Google Scholar 

  • Cheung WY (1982) Calmodulin — Schlüsselfigur im Zellgeschehen. Spektrum der Wissenschaft 8:36–45

    Google Scholar 

  • Dulbecco R, Elkington J (1975) Induction of growth in resting fibroblastic cell cultures by Ca2+. Proc Natl Acad Sci USA 72:1584–1588

    Article  CAS  PubMed  Google Scholar 

  • Kakiuchi S, Yamazaki R (1970) Calcium dependent phophodiesterase activity and its activating factor (PAP) from brain. Studies on cyclic 3′, 5′-nucleotide phophodiesterase (III). Biochem Biophys Res Comm 41:1104–1110

    Article  CAS  PubMed  Google Scholar 

  • Marmé D (1981) Kalzium, Calmodulin und ihre zelluläre Funktion. Biologie in unserer Zeit 11:71–77

    Article  Google Scholar 

  • Watterson DM, Harrelson Jr WG, Keller PM, Shariff F, Vanaman TC (1976) Structural similarities between the Ca2+-dependent regulatory proteins of 3′, 5′-nucleotide phosphodiesterase and actomyosin ATPase. J Biol Chem 251:4501–4513

    CAS  PubMed  Google Scholar 

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© 1988 Springer-Verlag Berlin Heidelberg

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Niedner, R., Mizumoto, T., Marmé, D., Wokalek, H., Vanscheidt, W. (1988). Die Bedeutung von Calmodulin und Kalzium für die Wundheilung. In: Haneke, E. (eds) Gegenwärtiger Stand der operativen Dermatologie. Fortschritte der operativen Dermatologie, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73751-0_10

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  • DOI: https://doi.org/10.1007/978-3-642-73751-0_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-19321-0

  • Online ISBN: 978-3-642-73751-0

  • eBook Packages: Springer Book Archive

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