Abstract
Grüntzig’s concept of using a cylindrical balloon to stretch and remodel the lumen of obstructed arteries has evolved into an effective therapy for large numbers of patients with atherosclerosis [1]. Because of technical improvements in balloon catheter design, particularly with respect to profile and balloon strength, very few subtotal obstructions cannot be reached, crossed, and dilated. Despite intensive research-and-development efforts, to date no laser, mechanical, or atherectomy technique has come close to achieving the efficacy of balloon dilatation. The two major limitations to the wider application of percutaneous transluminal angioplasty are acute vessel closure after balloon removal and the related problem of chronic lesion restenosis.
Keywords
- Neointimal Proliferation
- Federal Drug Administration
- Medial Smooth Muscle Cell
- Atherosclerotic Rabbit
- Stent Wire
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1989 Springer-Verlag Berlin Heidelberg
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Roubin, G.S., Gianturco, C., Robinson, K. (1989). Development of a Balloon-Expandable Flexible Coil for Intraarterial Stenting. In: Zeitler, E., Seyferth, W. (eds) Pros and Cons in PTA and Auxiliary Methods. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73736-7_23
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DOI: https://doi.org/10.1007/978-3-642-73736-7_23
Publisher Name: Springer, Berlin, Heidelberg
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