In Vitro Effect of Different Antimicrobial Agents on Il-2 Production and Il-2 Receptor Expression of Human Lymphocytes
Among the first events of lymphocyte activation are the synthesis and surface expression of a receptor for interleukin-2 (Il-2R). The action of Il-2 results from binding to its specific receptors inducing the proliferation of activated T cells. Resting lymphocytes do not express their growth factor receptors on their surface, only as a consequence of antigenic or mitogenic stimulation . Il-2 production and Il-2 receptor expression seem to be important in the development and termination of the T-cell immune response. I1–2R is also present on some activated B cells, and interaction of Il-2 with these receptors may play a role in B-cell growth and differentiation .
KeywordsPenicillin Streptomycin Macromolecule Ampicillin Tetracycline
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