A Multicapillary Distributed Model of Blood-Bone Exchange to Analyse Multiple Tracer Outflow Dilution Data
Multiple tracer outflow dilution (MTOD) experiments have been performed in our laboratories to study such exchange in which 125I-labelled albumin reference and 85Sr (Ca analogue), 86Rb (K analogue) diffusible tracers were injected together into Krebs-Ringer bicarbonate buffer which was infused through the tibial nutrient artery at a physiological rate of 2 ml/min; outflow samples were taken simultaneously every 5 s from the ipsilateral femoral vein over a period of 5 min (McCarthy and Hughes 1986).
KeywordsDiffusible Tracer Capillary System Final Parameter Estimate Outflow Sample Include Flow Rate
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