Abstract
The family Picornaviridae contains four genera: enteroviruses, cardioviruses, rhinoviruses, and aphthoviruses [26]. Enteroviruses that infect humans are polio, Coxsackie (CV) group A (CVA) and group B (CVB), echo, hepatitis A, and other enteroviruses. CV infections have been associated with a variety of human diseases, ranging from common cold to myocarditis, pericarditis, and juvenile onset (type I, insulin-dependent) diabetes.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Beatrice ST, Katze MG, Zajac BA, Crowell RL (1980) Induction of neutralizing antibodies by the coxsackievirus B3 virion polypeptide, VP2. Virology 104: 426–438
Brown F, Talbot P, Burrows R (1973) Antigenic differences between isolates of swine vesicular disease and their relationship to coxsackie B5 virus. Nature (London) 245: 315–316
Chatterjee NK (1988) Replication. In: Bendinelli M, Friedman H (eds) Coxsackieviruses: a general update. Plenum, New York, p. 35
Chatterjee NK, Nejman C (1985) Membrane-bound virions of coxsackievirus B4: cellular localization, analysis of the genomic RNA, genome-linked protein, and effect on host macromolecular synthesis. Arch Virol 84: 105–118
Chatterjee NK, Nejman C (1986) Protein kinase in nondiabetogenic coxsackievirus B4. J Med Virol 19: 353–365
Chatterjee NK, Nejman C (1988) Insulin mRNA content in pancreatic beta cells of coxsackievirus B4-induced diabetic mice. Mol Cell Endocrinol 55: 193–202
Chatterjee NK, Tuchowski C (1981) Comparison of capsid polypeptides of group B coxsackieviruses and polypeptide synthesis in infected cells. Arch Virol 70: 255–269
Chatterjee NK, Tuchowski C (1981) Translation of coxsackievirus B RNAs in a rabbit reticulocyte lysate: characterization of the genome RNA, reaction conditions for translation, and analysis of the products. Arch Viral 70: 271–283
Chatterjee NK, Samsonoff WA, Tuchowski C (1983) Isolation and characterization of a membrane-bound population of group B coxsackieviruses. J Virol 45: 832–841
Chatterjee NK, Haley TM, Nejman C (1985) Functional alterations in pancreatic beta cells as a factor in virus-induced hyperglycemia in mice. J Biol Chem 260: 12786–12791
Chatterjee NK, Nejman C, Gerling I (1988) Purification and characterization of a strain of coxsackievirus B4 of human origin that induces diabetes in mice. J Med Virol (in press)
Cords CE, James CG, McLaren LC (1975) Alteration of capsid proteins of coxsackievirus A 13 by low ionic concentrations. J Virol 15: 244–252
Crowell RL, Landau BJ (1983) Receptors in the initiation of picornavirus infections. In: Fraenkel-Conrat H, Wagner RR (eds) Comprehensive virology, vol 18. Plenum, New York, p 1
Gauntt CJ, Griffith MM, Sauck JR, Upson HR, Carlson EC (1975) Properties and origins of infectious rhinovirus type 14 particles of different buoyant densities. J Virol 16: 1265–1272
Gerling I, Nejman C, Chatterjee NK (1988) Coxsackievirus B4 infection in mice increases the expression of the 64K autoantigen and glucose sensitivity of the islets prior to the development of hyperglycemia. Diabetes (in press)
Harris TJR, Doel TR, Brown F (1977) Molecular aspects of the antigenic variation of swine vesicular disease and coxsackie B5 viruses. J Gen Virol 35: 299–315
Hartig PC, Madge GE, Webb SR (1983) Diversity within a human isolate of coxsackie B4: relationship to virus-induced diabetes. J Med Virol 11: 23–30
Holland JJ, Kiehn ED (1968) Specific cleavage of viral proteins as steps in the synthesis and maturation of enteroviruses. Proc Natl Acad Sci USA 60: 1015–1022
Iizuka N, Kuge S, Nomoto A (1987) Complete nucleotide sequence of the genome of coxsackievirus B1. Virology 156: 64–73
Jenkins O, Booth JD, Minor PD, Almond JW (1987) The complete nucleotide sequence of coxsackievirus B4 and its comparison to other members of the picornaviridae. J Gen Virol 68: 1835–1848
King AMQ, Sanger DV, Harris TJR, Brown F (1980) Heterogeneity of the genome-linked protein of foot-and-mouth disease virus. J Virol 34: 627–634
Korant BD, Lonberg-Holm K, Yin FH, Noble-Harvey J (1975) Fractionation of biologically active and inactive populations of human rhinovirus type 2. Virology 63: 384–394
Kiehn ED, Holland JJ (1970) Synthesis and cleavage of enterovirus polypeptides in mammalian cells. J Virol 5: 358–367
Lindberg AM, Stalhandske POK, Pettersson U (1987) Genome of coxsackievirus B3. Virology 156: 50–63
Matteucci D, Paglianti M, Giangregorio AM, Capobianchi MR, Dianzani F, Bendinelli M (1985) Group B coxsackieviruses readily establish persistent infection in human lymphoid cell lines. J Virol 56: 651–656
Matthews REF (1982) Classification and nomenclature of viruses. Karger, Basel, p 129
Melnick JL (1985) Enteroviruses: polioviruses, coxsackieviruses, echoviruses, and newer enteroviruses. In: Fields BN (ed) Virology. Raven, New York, p 739
Pallansch MA, Kew OM, Semler BL, Omilianowski DR, Anderson CW, Wimmer E, Rueckert RR (1984) Protein processing map of poliovirus. J Virol 49: 873–880
Prabhakar BS, Haspel MY, McClintock PR, Notkins AL (1982) High frequency of antigenic variants among naturally occurring human coxsackie B4 virus isolates identified by monoclonal antibodies. Nature (London) 330: 374–376
Schmidt NJ, Ho HH, Lennette EH (1975) Propagation and isolation of group A coxsackieviruses in RD cells. J Clin Microbiol 2: 183–185
Tracy S (1985) Comparison of genomic homologies in the coxsackievirus B group by use of cDNA: RNA dot-blot hybridization. J Clin Microbiol 21: 371–374
Tracy S, Liu HL, Chapman NM (1985) Coxsackievirus B3: primary structure of the 5′ non-coding and capsid protein-coding regions of the genome. Virus Res 3: 263–270
Webb SR, Loria RM, Madge GE, Kibrick S (1976) Susceptibility of mice to group B coxsackie virus is influenced by the diabetic gene. J Exp Med 143: 1239–1248
Webb SR, Madge GE (1980) The role of host genetics in the pathogenesis of coxsackievirus infection in the pancreas of mice. J Infect Dis 141: 47–54
Young NA (1973) Polioviruses, coxsackieviruses, and echoviruses: comparison of the genomes by RNA hybridization. J Virol 11: 832–839
Zeichhardt H (1986) Enteroviruses. In: Specter S, Lancz GJ (eds) Clinical virology manual. Elsevier, New York, p 283
Zeichhardt H, Wetz K, Willingmann P, Habermehl KG (1985) Entry of poliovirus type 1 and mouse Elberfeld (ME) virus into HEp-2 cells: receptor-mediated endocytosis and endosomal or lysosomal uncoating. J Gen Virol 66: 483–492
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Chatterjee, N.K. (1988). Replication, Molecular Biology, and Pathogenesis of Coxsackieviruses. In: Schultheiß, HP. (eds) New Concepts in Viral Heart Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73610-0_7
Download citation
DOI: https://doi.org/10.1007/978-3-642-73610-0_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-73612-4
Online ISBN: 978-3-642-73610-0
eBook Packages: Springer Book Archive