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Stimulus-Secretion Coupling in Neuroendocrine Systems pp 73–104Cite as

Coupling of Electrical Activity and Hormone Release in Mammalian Neurosecretory Neurons

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Part of the book series: Current Topics in Neuroendocrinology ((CT NEUROENDOCRI,volume 9))

Abstract

In the world of neurosecretion, the mammalian magnocellular neurons that secrete oxytocin and vasopressin provide excellent models for studying the relationship between electrical activity and hormone release. Their cell bodies are grouped in well-defined areas of the hypothalamus, the supraoptic and paraventricular nuclei; their axons leave the nuclei, course in the hypothalamo-neurohy-pophyseal tract and terminate in the neural lobe of the hypophysis. In the neurohypophysis, their secretory products are released directly into the bloodstream and thus can be readily assayed by various methods. These magnocellular neurons constitute, then, a system whose anatomical organization, products of secretion, and patterns of hormone release are rather well established.

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Author information

Authors and Affiliations

  1. Laboratoire de Neurobiologie des Comportements INSERM U176, University of Bordeaux II, 1 rue Camille Saint-Saens, Bordeaux, France

    D. A. Poulain & D. T. Theodosis

Authors
  1. D. A. Poulain
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  2. D. T. Theodosis
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Editors and Affiliations

  1. Pharmakologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 366, 6900, Heidelberg, Germany

    Detlev Ganten M.D., Ph.D.

  2. Rockefeller University, York Avenue, and 66th Street, New York, NY, 10021, USA

    Donald Pfaff Ph. D.

  3. Department of Anatomy, Medical School, Bristol, BS8 1TD, England, UK

    Brian Pickering Ph. D.

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© 1988 Springer-Verlag Berlin Heidelberg

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Poulain, D.A., Theodosis, D.T. (1988). Coupling of Electrical Activity and Hormone Release in Mammalian Neurosecretory Neurons. In: Ganten, D., Pfaff, D., Pickering, B. (eds) Stimulus-Secretion Coupling in Neuroendocrine Systems. Current Topics in Neuroendocrinology, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73495-3_3

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  • DOI: https://doi.org/10.1007/978-3-642-73495-3_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73497-7

  • Online ISBN: 978-3-642-73495-3

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