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Trauma Peptide T-Cell Suppression: Mechanisms of Action

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Book cover Immune Consequences of Trauma, Shock, and Sepsis

Abstract

Immunosuppression in trauma patients has been well documented by several groups. The causes of this suppression are at both the humoral and cellular level. Many of the described immunosuppressive effects can be induced in normal cells by coincubation with trauma serum, suggesting the presence of circulating immunosuppressive factors. The isolation and partial characterization of a low molecular weight peptide from the serum of trauma patients have been previously described [1].

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References

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© 1989 Springer-Verlag, Berlin Heidelberg

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Hoyt, D.B., Pinney, E., Ozkan, A.N. (1989). Trauma Peptide T-Cell Suppression: Mechanisms of Action. In: Faist, E., Ninnemann, J.L., Green, D.R. (eds) Immune Consequences of Trauma, Shock, and Sepsis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73468-7_37

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  • DOI: https://doi.org/10.1007/978-3-642-73468-7_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73470-0

  • Online ISBN: 978-3-642-73468-7

  • eBook Packages: Springer Book Archive

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