Abstract
The metabolic and neuroendocrine responses to injury are important parts of the stress reaction. They teleologically provide a better opportunity for a biologic organism to survive under adverse circumstances or when injured. John Hunter nearly two centuries ago described the reactions to injury as inducing “both the disposition and the means of cure.” This suggested that injury initiates a sequence of responses that are both the result of the injury as well as mechanisms by which the biologic organism can survive and heal the injury. The objective of this complex coordinated sequence of responses is maintenance of blood flow, oxygen delivery, organ perfusion, and mobilization and utilization of substrates for healing and recovery.
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© 1989 Springer-Verlag, Berlin Heidelberg
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Baue, A.E. (1989). Neuroendocrine Response to Severe Trauma and Sepsis. In: Faist, E., Ninnemann, J.L., Green, D.R. (eds) Immune Consequences of Trauma, Shock, and Sepsis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73468-7_3
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DOI: https://doi.org/10.1007/978-3-642-73468-7_3
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