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Severe Cystic Bone Lesions: Skeletal Manifestation of Mastocytosis or Special Kind of Primary Osteoporosis?

  • K. J. Woggan
  • H.-P. Kruse
  • G. Delling
  • F. Kuhlencordt
Conference paper

Abstract

Nettleship (1869) firstly described cutaneous mastocytosis as “an unusual form of urticaria”. Sangster (1877) called these lesions urticaria pigmentosa, Unna (1887) firstly recognized mast cell infiltrations to be responsible for this disease. The earliest description of the mast cells was made by Paul Ehrlich in 1879. For a long time mastocytosis was thought to be a benign cutaneous lesion only and so this term was used as a synonym of the clinical term urticaria pigmentosa. Since Bertelotti (1943) and Ellis (1949) described mast cell infiltrations in nearly all organ systems and Sagher et al. (1952) discovered the involvement of bones, mastocytosis was recognized as a potential systemic disease.

Keywords

Mast Cell Systemic Mastocytosis Iliac Crest Biopsy Spontaneous Fracture Skeletal Manifestation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • K. J. Woggan
  • H.-P. Kruse
  • G. Delling
  • F. Kuhlencordt

There are no affiliations available

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