Genetic Polymorphism of Urinary Pepsinogen (PGA) Detected by Immunoblotting

  • T. Yasuda
  • K. Kishi
Conference paper
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 2)


Pepsinogen is classified into two immunochemically distinct groups, PGA and PGC. PGA is detected in serum and urine as uropepsinogen, and while PGC is present in serum and seminal fluid. Genetic models of PGA have been proposed by several investigators (Samloff and Townes 1970; Taggart et al. 1979; Korsnes and Gedde-Dahl 1980; Frants et al. 1984), who have used all the proteolytic properties of acid-activated PGA for the detection of the isozymogens on agar or polyacrylamide gels. However, the complexities of these techniques have yielded a number of conflicting results, leading to various different genetic models.


Genetic Model Human Urine Seminal Fluid Blotting Transfer Normal Human Urine 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • T. Yasuda
    • 1
  • K. Kishi
    • 1
  1. 1.Department of Legal MedicineFukui Medical SchoolMatsuoka-cho, FukuiJapan

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