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Regulation of NaCl Transport in Tight Epithelia

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NaCl Transport in Epithelia

Part of the book series: Advances in Comparative and Environmental Physiology ((COMPARATIVE,volume 1))

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Abstract

Regulation by vertebrates of the amount of salt in the body is accomplished by the controlled transport of Na and Cl ions by various epithelial tissues. The amount of NaCl retained in the body determines, in turn, the volume of extra-and intracellular water, which must be maintained within narrow limits. This review will focus on the mechanisms controlling a specific transport process, the reabsorption of NaCl, by a class of high resistance epithelia represented by the mammalian cortical collecting tubule, the amphibian skin, the colon in mammals, amphibians, reptiles, and birds, and the urinary bladders of mammals, amphibians, and reptiles. These mechanisms involve modulations in the activities of ion channels, ion pumps, and metabolic processes. The major thesis of this chapter will be that different types of control mechanisms govern these processes on different time scales.

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  1. Department of Physiology, Cornell University Medical College, New York, NY, 10021, USA

    L. G. Palmer

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  1. Physiologisches Institut der Universität Freiburg, Hermann-Herder-Straße 7, 7800, Freiburg, Germany

    Rainer Greger

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Palmer, L.G. (1988). Regulation of NaCl Transport in Tight Epithelia. In: Greger, R. (eds) NaCl Transport in Epithelia. Advances in Comparative and Environmental Physiology, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73285-0_8

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  • DOI: https://doi.org/10.1007/978-3-642-73285-0_8

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