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Combinations of Antibiotics

  • Sabine Enenkel
  • Wolfgang Stille

Abstract

As a general principle, an infection should be treated with a single antibiotic. Combinations of antibiotics are only occasionally justified. The main bacteriological reasons for the use of combinations are:
  1. 1.

    To extend the spectrum of activity

     
  2. 2.

    To delay the development of resistance

     
  3. 3.

    To achieve synergy

     

Keywords

Clavulanic Acid Fixed Combination Antibiotic Combination Cumulative Toxicity Optimal Agent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Sabine Enenkel
    • 1
  • Wolfgang Stille
    • 2
  1. 1.Department of PediatricsUniversity Hospital, Johann Wolfgang Goethe-UniversitätFrankfurt/Main 70Germany
  2. 2.Department of Internal MedicineUniversity Hospital Johann Wolfgang Goethe-UniversitätFrankfurt/Main 70Germany

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